InnoCentive > Challenges > Global Health

Quantifying Microbial Contamination of Hard Surfaces

Tue, 14 May 2013 21:13:20 GMT

The Seeker is looking for a collaboration partner to provide or develop a viable, and extremely easy to use method to assess the microbial (bacterial & fungal) cleanliness of hard surfaces.

This is an electronic Request-for-Partners (eRFP) Challenge; the Solver will only need to submit a written proposal to be evaluated by the Seeker with a goal of establishing a collaborative partnership.

Challenge Reward: varies Deadline: Jun 28, 2013

Measuring Efficacy of Online Promotions

Thu, 02 May 2013 21:12:42 GMT

How can the Seeker track the influence of online promotions in achieving a pre-determined outcome ? The specific situation is disclosed within the detailed challenge description.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $5,000 USD Deadline: Jun 02, 2013

Male/Female Differences in the Pathogenesis and Presentation of Alzheimer’s Disease in Pre-symptomatic, Early Symptomatic and Late Stages

Fri, 26 Apr 2013 21:02:03 GMT

The Geoffrey Beene Foundation Alzheimer’s Initiative (GBFAI) is launching the 2013 Geoffrey Beene Global NeuroDiscovery Challenge whose goal is to identify male/female differences in the pathogenesis and presentation of Alzheimer’s disease (AD) in the pre-symptomatic, early symptomatic and late stages of AD. The objective of this Challenge is to generate novel hypotheses addressing the causes and consequences of such differences. The Solvers are also expected to provide a rationale supported by available data and a detailed research plan describing how to test the hypothesis. Of particular interest are hypotheses that can be validated in a secondary phase by mining existing AD databases for analysis of variables associated with biologic male/female differences in AD.

This Challenge requires only a written proposal.

Challenge Reward: $100,000 USD Deadline: Aug 31, 2013

Automated & Real-Time Probe Guidance Technology

Wed, 17 Apr 2013 11:19:19 GMT

The Seeker is looking for a collaboration partner to propose concepts for an automatable technology to signal accurate placement of a small (mm-scale) probe within a complex organic matrix.

Challenge Reward: varies Deadline: Jun 03, 2013

Innovative and/or Disruptive Products and Technologies

Fri, 12 Apr 2013 21:06:05 GMT

Procter & Gamble is looking for new products and technologies that can grow sales in traditional or emerging retail channels. Please submit your non-confidential information on new products and/or technologies that we may evaluate against our needs for potential collaborations with you.

This is an electronic Request-for-Partners (eRFP) Challenge; the Solver will only need to submit a written proposal to be evaluated by Procter & Gamble with a goal of establishing a collaborative partnership.

Challenge Reward: varies Deadline: May 27, 2013

GlaxoSmithKline Electroceutical Ideation Challenge

Thu, 11 Apr 2013 13:17:17 GMT

Bioelectronic medicines or “electroceuticals” promise to treat disease by modulating neural electrical impulses. Which specific disease has a major peripheral neural control component and would be the best proof of principle for such medicines?

You do not need to perform any experiments, only to describe the conceptual approach and need in a total of 3 pages!

This is an Ideation Challenge with a guaranteed award for at least one submitted solution. Solvers can also be considered for research funding.

Challenge Reward: $5,000 USD Deadline: May 11, 2013

LONP1 Protease: Seeking Knowledge, Methods or Validation

Tue, 12 Mar 2013 15:16:33 GMT

Lon proteases are a widely distributed family of serine proteases. LONP1 is a human protease that the Seeker hypothesizes may be a target relevant to cancer therapy.

Your insights are required regarding how LONP1 may be useful as a target for cancer therapies, or as to how the utility of LONP1may be assessed.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $7,500 USD Deadline: Apr 12, 2013

Clean Hands Save Lives - Evidence-Based Communication Strategies

Wed, 30 Jan 2013 22:33:54 GMT

The Seeker needs to understand how data recording compliance with hand disinfection best practice procedures can be effectively communicated in a way that motivates professionals to improve or maintain compliance. This isn’t just about the message, but the channel used to communicate, frequency of communication & tonality!

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $7,500 USD Deadline: Mar 04, 2013

Increasing Efficiency of Generating Statistically Relevant Control Group Data

Sat, 22 Dec 2012 16:11:26 GMT

The statistical value of treated (placebo) control groups is in demonstrating the safety and efficacy of a drug candidate in a population where variables and potential biases compared to the test patient population are minimized. How can the efficiency of randomized controlled clinical trials be increased by reducing the number of patients needed in control groups?

Proposals from individuals outside of clinical trials disciplines are highly desired – are you able to describe a statistical basis for a solution and its value in demonstrating treatment difference without impacting on the ability of data interpretation?

This Challenge requires only a written proposal.

Challenge Reward: $25,000 USD Deadline: Feb 21, 2013

Accurately Locating Fluid Loss in Complex Networks

Fri, 21 Dec 2012 19:38:05 GMT

The Seeker requires a method or technology that can accurately detect and position small losses of pressurized fluid from supply networks. Details regarding the limitations of the current methods, and others the Seeker has trialed, are included in the detailed challenge description.

This Challenge requires only a written proposal.

Challenge Reward: $20,000 USD Deadline: Feb 21, 2013

Home or ‘Point of Care’ Tests for Plasma Clotting Factors (VIII or IX)

Fri, 21 Dec 2012 19:16:23 GMT

The Seeker requires a test that could easily be used to monitor the level of blood coagulation factors FVIII or FIX present in hemophilia A and B patients, respectively. Today, many tests are commercially available, but none are suited for convenient testing either by care providers in the clinic or by hemophilia patients at home. A semi-quantitative test is required that would provide reliable information on the blood levels of FVIII or FIX relative to a state considered as ‘Normal’, ‘Mild’ or ‘Severe’ state of disease.

This Challenge requires only a written proposal.

Challenge Reward: $25,000 USD Deadline: Feb 21, 2013

Change from Curative to Preventive Products – How to Promote Word of Mouth Recommendations?

Wed, 21 Nov 2012 21:32:13 GMT

Ideas and concepts are required that will help promote word of mouth recommendations to help people move from on-demand products that address an existing problem to longer acting preventative products. Concepts and ideas based on expertise in almost any industry are relevant and applicable to this challenge!

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Dec 16, 2012

Highly Stable Formulation of Two Compounds with Differential Solubility

Wed, 21 Nov 2012 15:29:00 GMT

A stable aqueous formulation is required for a macrocyclic lactone in combination with another active ingredient that has a different solubility profile. Details of the precise active ingredients and other requirements are given in the body of the challenge description.

This Challenge requires only a written proposal.

Challenge Reward: $25,000 USD Deadline: Jan 21, 2013

Partnering to Develop the NEXT DNA Sequencing Technology

Mon, 19 Nov 2012 15:01:19 GMT

The Seeker is a global company looking for truly novel ‘Next Generation Sequencing’ technologies that it can help to co-develop or in-license. A description of the technology is required, along with any existing data to support proof-of-concept.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $15,000 USD Deadline: Dec 19, 2012

Detecting Isocyanates in Suspended Particles

Fri, 16 Nov 2012 14:45:36 GMT

A detection technology capable of sensitive detection of isocyanates in an aqueous suspension of organic, liquid-containing microparticles is required. More details regarding the sample matrix and assay features are in the detailed challenge description.

This Challenge requires only a written proposal.

Challenge Reward: $25,000 USD Deadline: Jan 16, 2013

A Diabetic Cookie That Tastes Like the ‘Real Thing’

Fri, 16 Nov 2012 10:21:37 GMT

A recipe for a diabetic cookie is required - a low glycemic index (GI), low calorie cookie.

The cookie should provide a taste and mouth feel experience directly comparable to a conventional non-diabetic cookie.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $5,000 USD Deadline: Dec 17, 2012

Novel Biodegradable Hydrophilic Polymers

Tue, 13 Nov 2012 16:22:08 GMT

Novel hydrophillic polymers that are both biocompatible and biodegradable by mammalian enzymes are required. It is important that the proposed polymers are amenable to controlled synthesis so that a defined molecular weight range can be achieved.

This Challenge requires only a written proposal.

Challenge Reward: $35,000 USD Deadline: Jan 13, 2013

Understanding Bioavailability of Peptides

Fri, 09 Nov 2012 16:09:15 GMT

What sequence and structural factors influence the bioavailability of small peptides following ingestion? Which physiological parameters determine whether peptides reach and persist in the systemic circulation, and which models would be relevant to assess peptide bioavailability? The Seeker is looking for insightful submissions that are supported by peer-reviewed publications, in-silico modelling &/or existing research data.

This Challenge requires only a written proposal.

Challenge Reward: $20,000 USD Deadline: Jan 09, 2013

GlaxoSmithKline Challenge: Explaining Unusual Toxicity

Tue, 06 Nov 2012 21:18:17 GMT

Can you help GlaxoSmithKline to explain an unusual and unexpected toxicity profile in a rat model?

Additional information is available and linked from the challenge description. GSK is looking to work with Solvers who can offer novel insights and demonstrate their expertise. This challenge is open to all – from biochemists through to zoologists!

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Dec 09, 2012

PXE – Evaluating Hypotheses and Suggesting Experiments for a Rare Disease

Wed, 31 Oct 2012 16:39:10 GMT

The Seeker, PXE International, the primary group responsible for funding PXE research, presents two existing hypotheses (an active circulating metabolite(s) or a tissue-specific dysfunction) for the rare disease Pseudoxanthoma Elasticum (PXE). The Seeker requests that Solvers present evidence favoring one of the two hypotheses, then provide additional experiments to conduct to further knowledge around the disease mechanism.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution. In addition to the Challenge award, PXE International will also assist finalists in efforts to obtain funding for PXE-related research.

Challenge Reward: $7,000 USD Deadline: Nov 30, 2012

Topical Methods to Prevent Yeast Infections

Mon, 29 Oct 2012 13:18:48 GMT

Topical treatments or materials are required that prevent overgrowth of Candida specieson human skin (dermis or mucosa). A wide range of potential solutions are in scope – from liquid applications to functional materials that retard yeast growth on skin.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Dec 18, 2012

Measuring Central Nervous System Development in Infants & Children

Fri, 05 Oct 2012 18:29:41 GMT

How can we reproducibly and easily measure central nervous system (CNS) development during the most important years of a child’s life? Detailed proposals of markers or measurements are required that provide significant advances compared to current methods.

This Challenge requires only a written proposal.

Challenge Reward: $25,000 USD Deadline: Dec 15, 2012

Storage Container that Protects Seed and Grain from Rodents

Fri, 21 Sep 2012 12:58:02 GMT

This Challenge seeks designs or materials for a storage bag, container, or vessel that protects seeds and grains against rodent infestations. Key requirements include: durability over several seasons, low cost, and feasibility for use in developing nations.

This Challenge requires only a written proposal.

Challenge Reward: $20,000 USD Deadline: Nov 21, 2012

Improving Health by Increasing Use of Preventive Care

Thu, 20 Sep 2012 16:05:59 GMT

This Challenge seeks to identify strategies for improving healthcare outcomes by increasing the use of preventive-care services. This Challenge specifically targets the use of these services by people in the United States who receive federal- or state-funded healthcare, however, insight from Solvers in other countries with different health systems may be very applicable.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $7,000 USD Deadline: Oct 22, 2012

Cell Based Assay for Amino Acid Deprivation Response

Fri, 31 Aug 2012 19:22:35 GMT

A novel strategy to make a cell based assay is required. The resulting assay should allow the amino acid deprivation response (AAR) to be quantifiably measured in a high throughput screening program for modulators of the pathway.

This Challenge requires only a written proposal.

Challenge Reward: $10,000 USD Deadline: Oct 01, 2012

Feeding the World in 2050 - What Challenges Will Agricultural Technologies Need to Meet?

Mon, 27 Aug 2012 19:12:19 GMT

What are the technical revolutions that agriculture needs to undergo in the next 20-35 years so the global population can be fed? You don’t need to describe the solution, but you do need to describe the unmet need and give some background to justify that need. The most novel and insightful ideas will be awarded.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $8,000 USD Deadline: Sep 27, 2012

Modifying Sensory Qualities of Vegetable Oil Formulations for Personal Care Products

Fri, 27 Jul 2012 16:47:11 GMT

A method or formulation is required that retains the benefits of vegetable oil cosmetic products, yet reduces the undesirable qualities e.g. stickiness and high cost.

This Challenge requires only a written proposal.

Challenge Reward: $20,000 USD Deadline: Sep 27, 2012

AARP Foundation/InnoCentive : Drive to End Hunger – Elimination of Food Deserts

Mon, 23 Jul 2012 17:50:51 GMT

AARP Foundation, in collaboration with InnoCentive, is soliciting ideas to help eliminate/reduce food deserts in the United States. Solutions should be long term and self-sustaining.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Sep 20, 2012

AARP Foundation/InnoCentive : Drive to End Hunger – Sustainable Solutions

Mon, 23 Jul 2012 17:50:31 GMT

AARP Foundation, in collaboration with InnoCentive, is soliciting ideas to combat hunger in the aging population in the United States. In 2009, nearly 9 million older adults (50 and older) experienced food insecurity or did not know where their next meal was coming from. The number of food insecure older adults has been steadily increasing since 2007. Ideas or programs should focus on long-term, self-sustaining solutions that prevent/reduce food insecurity for older adults.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Sep 20, 2012

Advancing Research into Facial Fat Redistribution

Fri, 20 Jul 2012 17:09:35 GMT

Distribution of subcutaneous fat pads changes as people age. Despite the vast amount of research into obesity and the physiology of adipose tissue creation, relatively little is understood regarding the physiology of how fat pads within the face are built up or reduced over time.

The Seeker is looking to enable better research into facial fat pad modulation and requires insights relevant to any one of 3 possible solution paths. The Seeker intends to make 3 awards, one to each of the ‘best in class solutions’. More information is available within the detailed challenge description.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Sep 03, 2012

Liquid Handling Automation for Slurry Formation

Tue, 17 Jul 2012 14:28:19 GMT

The Seeker requires an automated workflow for the formation of homogeneous aqueous slurries from powders. Slurry volumes are approximately 250 ml. Proposals are required describing how commercially available laboratory instruments may be integrated to enable automated formation of powder slurries.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $8,000 USD Deadline: Aug 31, 2012

Real-Time Differentiation of Retina from RPE & Choroid

Mon, 16 Jul 2012 20:37:56 GMT

How can the choroid and retina be distinguished in real time using a non-destructive and label-free technology? The objective is to identify sensor technologies that could be used at the tip of an instrument. More information is provided in the detailed challenge description.

This Challenge requires only a written proposal.

Challenge Reward: $30,000 USD Deadline: Sep 16, 2012

My Air, My Health: An HHS/EPA Challenge

Tue, 05 Jun 2012 19:25:14 GMT

How do we connect personal devices for testing and reporting of both air quality and linked physiological data? Such a system would enable not only high-resolution mapping of pollutant concentrations, but also support research and reporting of individual physiological responses related to the pollutant.

The U.S. Environmental Protection Agency (EPA) and U.S. Department of Health and Human Service (HHS) [National Institute of Environmental Health Sciences (NIEHS) and Office of the National Coordinator for Health Information Technology (ONC)] envision a future in which powerful, affordable, and portable sensors provide a rich awareness of environmental quality, moment-to-moment physiological changes, and long-term health outcomes. Health care will be connected to the whole environment, improving diagnosis, treatment, and prevention at all levels.

This challenge is open only to Solvers who are individuals, teams or businesses with their permanent residences or primary places of business in the United States. More details are included in the challenge description.

Phase 1 of this Challenge requires only a written proposal.

Challenge Reward: $160,000 USD Deadline: Oct 05, 2012

Markers of Double Stranded DNA Breaks in Humans

Tue, 29 May 2012 15:18:12 GMT

Proposals of novel and detectable physiological markers of DNA double-strand breaks (dsb) in humans are required. The markers should be specific for detection of dsb or detection of DNA repair proteins associated with the repair of dsb. More details are included in the Challenge Description.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Jul 31, 2012

Cleveland Clinic: Modeling Fluid Loss in a Highly Branched Network of Vessels

Thu, 17 May 2012 19:42:07 GMT

The Seeker wishes to build a model that will predict the scale of fluid loss resulting from damage to a highly branched network of conduits. Several obvious variables such as vessel diameter are known to influence the scale of fluid loss. The Seeker wishes to incorporate less obvious factors in a model that has a high predictive accuracy. More contextual details are included in the detailed challenge description.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Jun 17, 2012

Optical Measurements of Inflammatory Markers

Wed, 16 May 2012 22:35:35 GMT

The Seeker requires proposals describing optical or spectroscopic measurement technologies that have been, or could be, applied to measuring physiological markers of inflammation in living organisms. Proposals supported by citations from the literature (patent, commercial & scientific) are requested.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $7,500 USD Deadline: Jun 16, 2012

Spectroscopic Measurements of Skin Physiology

Wed, 16 May 2012 22:35:09 GMT

The Seeker requires proposals or reviews of spectroscopic measurement technologies that could be applied to measuring physiological markers in skin.. The goal is to enable measurement of markers at the molecular or cellular level. Gross measurements of morphology, color or temperature are not of interest. Comprehensive reviews or proposals supported by citations from the literature (patent, commercial & scientific) are preferred.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $7,500 USD Deadline: Jul 02, 2012

Stand Alone Field Measurement of Atmospheric Benzene & Butadiene

Wed, 04 Apr 2012 15:05:33 GMT

A method or technology is required that will enable sensitive, reproducible and rapid field-based monitoring of atmospheric benzene & 1,3 butadiene at low concentrations. These potent toxins needs to be detected in very low concentrations and the most sensitive methods of analysis currently require laborious sample collection and processing using laboratory-based instruments.

This Challenge requires only a written proposal.

Challenge Reward: $30,000 USD Deadline: Jun 04, 2012

Early Diagnostic Tools for Pancreatic Cancer

Wed, 29 Feb 2012 15:30:54 GMT

This Challenge, sponsored by Sandler-Kenner Foundation, seeks diagnostic tools for identification of pancreatic cancer at early stages of development.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Mar 31, 2012

Reducing Fat Absorption in Battered Fried Foods

Tue, 07 Feb 2012 19:08:58 GMT

This Challenge seeks to identify a method for reducing the absorption of fat into battered fried foods. A solution to this Challenge could have a tremendous effect on dietary health. The Seeker will strongly consider further collaborative research with the winner(s) of this Challenge.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $8,000 USD Deadline: Mar 07, 2012

Recovering Bacillus Spores from Swabs

Thu, 05 Jan 2012 20:01:12 GMT

The Seeker requires protocols for efficient recovery of bacterial spores (Bacillus subtilis/Bacillus atrophaeus) from pre-wetted surface sampling tools with handle. Guidance and standardized protocols are provided within the detailed challenge description.

This is a Reduction-to-Practice Challenge that requires a written proposal and experimental proof-of-concept data.

Challenge Reward: $30,000 USD Deadline: Apr 05, 2012

Models Motivating and Supporting Altruism Within Communities

Thu, 15 Dec 2011 15:23:13 GMT

Situations where someone is dependent on someone else to help manage everyday life are very common. We can see these situations in bringing up a child, in the support of individuals with functional disorders, support of family members with special care needs, and in the care of elderly relatives. The care demand varies case by case, but when the dependency increases the burden of the carer increases as well. It is a situation where you cannot choose, you have to handle the consequences of the development. For the carer it is often time consuming, expensive, and stressful and affects the quality of life for everyone involved. Family members are not always able to support each other as much as is needed. We are interested in looking at novel concepts from nature, business, or other areas that may elucidate the dynamics that help promote and maintain altruistic behaviors.

Challenge Reward: $8,000 USD Deadline: Jan 25, 2012

Foundation for Prader-Willi Research: Advancing Appetite and Satiety Research

Thu, 15 Dec 2011 11:01:20 GMT

The Foundation for Prader-Willi Research wishes to identify novel avenues for research and therapies to tackle the problem of hyperphagia and resulting obesity in Prader-Willi Syndrome (PWS). The Foundation intends to identify individuals with novel and convincing insights and proposals so that collaborative research opportunities can be identified. Simple literature reviews are not desired – truly novel insights into the mechanisms of hyperphagia in PWS and possible interventions/treatments are required.

Challenge Reward: $8,000 USD Deadline: Jan 26, 2012

London School of Hygiene and Tropical Medicine Challenge: Better Pit Latrines using Black Soldier Fly Larvae

Fri, 09 Dec 2011 12:18:03 GMT

This Challenge is sponsored by the London School of Hygiene and Tropical Medicine as part of its Sanitation Ventures project (http://www.sanitationventures.com/) funded by the Bill & Melinda Gates Foundation. This Challenge seeks a solution that will enable the contained presence of black soldier fly (BSF) larvae in existing pit latrines so they can digest waste and reduce latrine fill rates. Such solutions will greatly enhance the lives of people who live in the most vulnerable communities in developing countries for whom pit latrines are often their only sanitation choice.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Jan 19, 2012

Solid-Phase Detection of Bacteria & Viruses

Tue, 29 Nov 2011 17:51:23 GMT

A technology that enables detection of biological materials such as bacteria and viruses is required. The technology must be amenable for integration into solid-phase consumer products that are used by non-specialists.

This Challenge requires only a written proposal.

Challenge Reward: $30,000 USD Deadline: Jan 29, 2012

Increasing the Affordability of Inactivated Poliovirus Vaccine in Low- and Middle-income Countries

Thu, 10 Nov 2011 16:12:03 GMT

The goal of this Challenge is to identify problems or opportunity areas where eventual solutions might significantly reduce the cost of inactivated polio vaccine (IPV) use in low- and middle-income countries.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $25,000 USD Deadline: Jan 20, 2012

Medical Device Market Access Models for India

Tue, 27 Sep 2011 12:12:46 GMT

How can commercial medical devices be made available to large segments of the rural population in India? The Seeker is looking for business models based on proven examples that will enable high-value technologies to be marketed to both low- and mid-income Indian individuals and communities. The scope of the challenge is broad and a wide range of strategies are welcomed.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Oct 27, 2011

A GRI (Glucose Responsive Insulin) for Better Treatment of Type 1 Diabetes

Tue, 06 Sep 2011 21:10:39 GMT

This Challenge, sponsored by the Juvenile Diabetes Research Foundation International (JDRF) (the Seeker), is looking for novel ideas for the development of “glucose-responsive insulin”, an insulin that would work only when the body needs it, and deliver the precise amount of insulin activity in response to circulating glucose levels to control and maintain normal blood glucose levels throughout a daily routine with once-daily or less frequent dosing in people with insulin-dependent diabetes. JDRF envisions that the Winning Solution (or Solutions) from this Challenge will be further developed in a second phase that may involve the Winning Solvers and potentially partners from the commercial sector.

This Challenge requires only a written proposal from the Applicant (Solver).

Challenge Reward: $100,000 USD Deadline: Nov 09, 2011

Mechanical Joint with High Ultrasound Conductivity

Tue, 30 Aug 2011 18:58:29 GMT

A design for a mechanical joint mechanism is required. A cylindrical shaft that transmits ultrasonic energy must be joined to a disposable element. The joint mechanism must conduct ultrasound energy at high efficiency to the disposable element and the cylindrical shaft must be reusable.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Oct 01, 2011

Small Volume Blood Collection Without Haemolysis

Thu, 25 Aug 2011 15:54:53 GMT

The Seeker requires mechanisms that will allow collection of blood from the fingers and/or hand.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Sep 25, 2011

Raising Treatment Rate for Hepatitis C

Wed, 22 Jun 2011 15:41:48 GMT

The ultimate goal of this Challenge is to facilitate a sustainable increase in the treatment rate and in the number of treated patients with Hepatitis C in Europe.

This Challenge requires only a written proposal.

Challenge Reward: $15,000 USD Deadline: Aug 22, 2011

Communication Platform to Connect Vulnerable Communities with Climate Change Solutions

Tue, 12 Apr 2011 19:19:51 GMT

Local communities across the globe will need to adapt to changing climate conditions over the next years and decades. In doing so, they may be facing rising sea levels, public health concerns, water scarcity, floods, heat waves and more extreme weather, among other impacts.

Communities are facing many of these challenges today and there are several databases and initiatives with information about climate local impacts and needs. However, communication gaps often prevent connections between communities and the private sector and policy makers who can help serve and support community needs.

How could communication tools help collect, aggregate, share, and meet these needs? How could stronger connections help drive new local investments and markets for locally-appropriate goods and services in these communities?

We are searching for ideas of innovative communication platforms that will connect information about local community needs to public and private sector organizations that can provide solutions and support. A successful communication platform will establish the tools and incentives for communities and solution providers to identify, prepare for, and adapt to the impacts of climate change.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Jul 12, 2011

A Communication Platform to engage the “Hidden Community” of Family Caregivers

Thu, 31 Mar 2011 17:49:39 GMT

There are more than half a billion people taking care of someone elderly at home worldwide and the number is growing. Most of these dedicated "at-home" caregivers are not professionally trained to deal with such things as dementia, personal hygiene, medical conditions and complications. Our investigations lead us to believe that this "Hidden Community" would benefit greatly from educational materials, product information /recommendations and established healthcare techniques. We are looking for a "communication platform" to reach out to these individuals to provide educational information and respond to feedback to meet their needs.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $8,000 USD Deadline: May 02, 2011

European Business Model for Customer-Driven Regulated Markets

Thu, 31 Mar 2011 15:06:06 GMT

An organizational model is required that will allow an organization to better anticipate and respond to the demands of regulatory authorities and customers across the different EU regions.

This Challenge requires only a written proposal.

Challenge Reward: $20,000 USD Deadline: May 31, 2011

Educating About the Importance and Acceptance of Purifying Drinking Water

Sun, 27 Mar 2011 19:47:26 GMT

ITT Watermark, represented in this challenge by ITT Residential & Commercial Water, strives to bring clean, safe water to people in developing countries. With this Challenge they would like suggestions for addressing one of the biggest problems they encounter in this process – namely, that of educating illiterate populations about the importance of purifying drinking water. This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $5,000 USD Deadline: Apr 27, 2011

Delayed Release Formulation for Aqueous Protein Solution

Wed, 02 Feb 2011 22:20:12 GMT

A delayed release technology is required for a boosting agent that would allow the simultaneous delivery of both the prime agent and the boosting agent during a single vaccination. The boosting agent would be released only 10-20 days post injection.

This Challenge requires only a written proposal.

Challenge Reward: $40,000 USD Deadline: Apr 02, 2011

Delivery Device for High Viscosity Formulations

Mon, 17 Jan 2011 18:24:57 GMT

The Seeker desires designs for a device that will allow for the accurate and precise, subcutaneous delivery of a highly viscous formulation. This Challenge requires only a written proposal.

Challenge Reward: $20,000 USD Deadline: Mar 17, 2011

Thresholds for Perception of Color Differences

Fri, 17 Dec 2010 19:06:47 GMT

Physical appearance (color) is a critical attribute for pharmaceutical product quality. While color changes can be measured accurately and quantitatively by laboratory instruments, it is unclear how to correlate these quantitative data with an individual's subjective perception of color. How do we understand / correlate a subjective measure, that is, the level of change that can be detected by individuals (resulting in a product complaint) with a quantitative measurement?

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Jan 17, 2011

Mathematical Model to Estimate Patient Burden in Clinical Trials

Wed, 15 Dec 2010 22:13:38 GMT

The goal of this Challenge is to design a mathematical model to estimate the level of burden that participation in a clinical trial would place upon a patient.

This Challenge requires a written proposal and code.

Challenge Reward: $15,000 USD Deadline: Feb 16, 2011

Oligodendrocyte Precursor Immortalized Cell Line

Fri, 19 Nov 2010 19:43:58 GMT

A conditionally immortalized oligodendrocyte precursor cell line is required to advance research into therapies for multiple sclerosis (MS).

This is a Theoretical Challenge which requires a written proposal only. Awards will be made at the discretion of the Seeker after theoretical evaluation of the submissions. The Seeker retains the right to make partial awards should the awarded solution not meet all the Technical Requirements or Project Criteria. The Seeker wishes to engage successful Solvers to implement winning submissions and deliver cell lines in a second phase of this Challenge.

Challenge Reward: $20,000 USD Deadline: Jan 19, 2011

Reduce Infant Mortality by Fortifying Staple Foods with Folic Acid at the Home or Community Level

Fri, 12 Nov 2010 13:38:39 GMT

This Challenge sponsored by Scientists Without Borders is looking for low-cost, effective methods to fortify or supplement staple foods with folic acid for consumption by young women of child-bearing age in developing countries. Folic acid is critical for prevention of neural tube defects during pregnancy and for women's health overall.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Dec 13, 2010

How Could We Help People with Diabetes Better Manage their Disease?

Thu, 11 Nov 2010 19:18:39 GMT

The goal of this Challenge is to ask people with Diabetes Type 1 what can be done to make their daily routine of handling the disease (i.e. measuring blood glucose level and dosing insulin) easier.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Dec 12, 2010

Extraordinary & Unorthodox Philanthropy

Mon, 18 Oct 2010 19:07:30 GMT

The Seeker is looking for novel, unorthodox, and extraordinary opportunities for philanthropic investment. This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Nov 18, 2010

Improving Therapeutic Targeting of Bevacizumab

Mon, 04 Oct 2010 17:44:16 GMT

The Seeker requests novel biomarkers of response to the anti-angiogenic biologic therapy Bevacizumab. For this Theoretical Challenge, Solvers should provide pen and paper solutions describing their ideas for a biomarker.

Challenge Reward: $50,000 USD Deadline: Dec 04, 2010

Models for Sourcing Regional Food Databases

Thu, 30 Sep 2010 20:01:11 GMT

The Seeker wishes understand potential models for sourcing and integrating reliable and validated regional food databases. Various food analysis databases exist, but the seeker requires models of how these may be networked or integrated to provide consolidated information that is useful to diabetes patients around the world who wish to balance their diet and insulin intake.

This is an Ideation Challenge with a guaranteed award pool of $10,000. The best proposal will receive $5,000 and 1-3 additional awards will be made from the remaining $5,000.

Challenge Reward: $10,000 USD Deadline: Oct 30, 2010

Collaborative Activist Network for Better Health Care

Fri, 24 Sep 2010 19:30:18 GMT

The goal of this Challenge sponsored by the Joseph H. Kanter Family Foundation is to generate innovative ideas for creating an activist network of patients, medical professionals, and the general public, focused on promoting a patient-centered learning health system in which decisions are informed by patient outcome data generated as a byproduct of delivering care.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $5,000 USD Deadline: Dec 10, 2010

Urinary Biomarkers for Lupus Nephritis

Wed, 15 Sep 2010 18:35:50 GMT

The Seeker wishes to identify an alternative urine marker, or a combination of markers, for the prediction of renal flares and prognosis in lupus nephritis. This is an Ideation Challenge with a guaranteed award of $ 10,000 USD.

Challenge Reward: $10,000 USD Deadline: Oct 15, 2010

Novel Therapeutic Concepts to Treat Cancer

Wed, 15 Sep 2010 18:30:59 GMT

The Seeker is looking for novel, breakthrough, therapeutic concepts in the field of oncology. This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $10,000 USD Deadline: Oct 15, 2010

New Innovative Prophylaxis Approaches to Protect Against OP Pesticide Poisoning

Wed, 01 Sep 2010 17:36:12 GMT

The Seeker is looking for an innovative approach or several simultaneous approaches to identify compounds and prophylactic interventions that could be developed into new therapeutics or treatments which would provide enhanced protection against organophosphorus pesticide (OP) poisoning.

Challenge Reward: $15,000 USD Deadline: Dec 01, 2010

Improving the First 20 Years of Human Health

Fri, 13 Aug 2010 20:51:06 GMT

NASA, USAID, Department of State, and NIKE joined together to host LAUNCH in an effort to identify, showcase and support innovative approaches to sustainability challenges through a series of forums. LAUNCH searches for visionaries, whose world-class ideas, technologies or programs show great promise for making tangible impacts on society. Through the next Launch series, ten innovators and 40 thought leaders will come together to address an issue that affects every human: health.

Sustaining quality of life on Earth and in space requires transformative advances in science and technology, along with new models, policies and behaviors that will guide human development. The search for innovative technology solutions to ensure healthy astronauts orbiting the planet mirrors healthcare challenges faced by providers throughout the world. The same requirements for simple, rugged, ultra portable, low power devices to provide remote diagnostic capability serves dual needs for humans living within the extreme environments on and off the planet. Targeting preventative health measures within the first twenty years of life offers a unique opportunity to change the human condition for this and future generations.

LAUNCH seeks innovations that are preventive with a focus on nutrition, exercise, and health care Specifically, LAUNCH is seeking innovations in providing and improving:

Optimal nutrition (access, choice, and quality of nutritious food and required nutrients)
Regular participation in physical activity and healthy lifestyle choices.
Participation in primary preventive health care including supporting infrastructure, such as diagnostic and monitoring technology

Challenge Reward: varies Deadline: Sep 13, 2010

Chordoma Cancer Cell Lines Needed to Save Lives!

Tue, 13 Jul 2010 21:58:24 GMT

The Chordoma Foundation requests cell lines or animal models that can be used for research into chordoma - a slow growing bone cancer that is often resistant to radio- and chemotherapies.

This Challenge has now been opened to include animal models and the deadline has been changed to a 3 month rolling deadline. This innoCentivee Challenge will close once the Seeker has 3 submissions to evaluate, but the Chordoma Foundation will continue to incentivize research into Chordoma and potential therapies.

Challenge Reward: $10,000 USD Deadline: Mar 07, 2012

Biomarkers for Progressive Multifocal Leukoencephalopathy (PML)

Mon, 21 Jun 2010 20:32:11 GMT

This Challenge requires suggestions for biomarkers predictive of Progressive Multifocal Luekoencephalopathy (PML).

This is a Theoretical Challenge that requires only a written proposal to be submitted. The Challenge award will be contingent upon theoretical evaluation of the proposal by the Seeker. The Seeker reserves the right to make partial awards to Solvers in exchange for non-exclusive rights.

Challenge Reward: $40,000 USD Deadline: Aug 22, 2010

JC Virus or Polyoma Virus Animal Model

Tue, 25 May 2010 12:28:44 GMT

An animal model is required which allows replication of JC virus. The Seeker requires a theoretical proposal with a detailed strategy how to step-wise develop and test the animal model. A non-human cell-culture/tissue model allowing JC virus replication would also be considered.

Successful Solvers exhibiting sufficient knowledge and ability may be asked to enter a contract research agreement with the Seeker to develop such an animal model. This is a Theoretical Challenge and requires only a pen & paper solution.

Challenge Reward: $40,000 USD Deadline: Jul 25, 2010

Replacing Ag/AgCl for In-Vivo Reference Electrodes

Wed, 31 Mar 2010 13:44:58 GMT

The Seeker wishes to identify conductive materials feasible for use in a reference electrode. The material should be suitable for in vivo physiological measurements.

This is a Theoretical Challenge that requires only a written proposal to be submitted. The Challenge award will be contingent upon theoretical evaluation of the proposal by the Seeker.

Challenge Reward: $15,000 USD Deadline: May 30, 2010

Rapid Therapeutic Development Pipeline

Wed, 10 Mar 2010 22:18:02 GMT

The Seeker requires an achievable strategy for evolving species-specific therapies for unknown bacterial isolates within as little as seven days after receiving a culturable sample.

This is an Ideation Challenge so your creativity and experience qualify you to participate in this challenge. Responses are expected to be about 2-3 written pages not including figures, however there is no strict limit on length.

Challenge Reward: $10,000 USD Deadline: Jun 10, 2010

Help Reduce the Placebo Effect in Clinical Drug Trials!

Wed, 10 Feb 2010 21:37:42 GMT

Markers predictive of placebo-responders in clinical drug trials, or rational for improved trial designs, are required in order to increase the efficacy of clinical drug trials and better understand the effects of human therapies.

This is a Theoretical Challenge that requires only a written proposal to be submitted. The Challenge award will be contingent upon theoretical evaluation of the proposal by the Seeker.

Challenge Reward: $25,000 USD Deadline: Apr 10, 2010

Design of a Solar Water Treatment System based on TiO2 Nanoparticles

Mon, 08 Feb 2010 20:00:08 GMT

The Rockefeller Foundation is providing support to this Seeker for the design of a low cost water treatment system based on solar radiation and titanium dioxide (TiO2). It is part of the Global Giveback Innovation Challenge Set. A prototype design will be required using known proven technology supplied by the Seeker.

Challenge Reward: $15,000 USD Deadline: Apr 08, 2010

What Do We Not Know to Cure Type 1 Diabetes?

Fri, 29 Jan 2010 21:01:35 GMT

This Challenge is asking InnoCentive Solvers to formulate well-defined problems aimed at advancing our knowledge about Type 1 Diabetes and ultimately eradication of the disease. This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $5,000 USD Deadline: Mar 15, 2010

Potential Drug Targets for Kinetoplastid Infectious Diseases

Thu, 28 Jan 2010 15:53:14 GMT

The Drugs for Neglected Diseases initiative (DNDi), is looking for potential drug targets for kinetoplastid infectious diseases affecting the developing world (African Sleeping Sickness, Visceral Leishmaniasis, Cutaneous Leishmaniasis, and Chagas Disease). The focus is on chemically validated targets and associated small molecules.

This Challenge requires only a written proposal.

Challenge Reward: $10,000 USD Deadline: Apr 16, 2010

Design of a Low Cost Rainwater Harvesting Storage Tank in a Wetland Region

Mon, 11 Jan 2010 19:33:05 GMT

The Rockefeller Foundation is providing support to this Seeker for the design of a new rainwater harvesting storage tank for use in a wetland Region in India. It is part of the Global Giveback Innovation Challenge Set. The tank needs to be affordable by the local people and have a capacity of 6000 liters. High water table, flooding, differential settlement and acidic soil are just some of the issues to be overcome with the proper design.

Challenge Reward: $20,000 USD Deadline: Mar 11, 2010

Aircraft Interior Space Sampling Methodology

Wed, 30 Sep 2009 14:06:47 GMT

We are searching for an aircraft interior space sampling and analysis methodology to determine if aircraft interior is at or below a cleanliness standard for contagious diseases. We would like to gather ideas on what, where and how to sample as well as methods of analysis that could be fast and as simple as possible.

This is an Ideation Challenge so your creativity and experience qualify you to participate in this Challenge. Responses are expected (but not limited) to be about 2-3 written pages not including figures. You do not have to meet every requirement to be eligible for an award. A good solid answer that is part of the solution would still be considered.

Challenge Reward: $10,000 USD Deadline: Nov 30, 2009

New Methods for Detecting Pathogens

Thu, 27 Aug 2009 22:06:04 GMT

Surveying and maintaining the safety of air in crowded, public spaces is extremely important for public health. Areas in which large numbers of people spend extended amounts of time, such as airplanes, buses, subway stations, etc. must be carefully monitored to ensure that any communicable disease outbreaks (e.g. Swine Flu) or natural or manmade threats are detected and addressed rapidly.

This Challenge is seeking new ideas for methods of detecting pathogens within an airplane cabin environment. The Seeker is looking for novel ideas for platform technologies that they may be able to be used for this purpose. The pathogens of interest include dangerous biological agents, such as bacteria and viruses. Ideally a single platform could be used to detect all such airborne pathogens, but it’s possible that some platforms may only operate effectively for one or a few applications.

This is an Ideation Challenge so your creativity and experience qualify you to participate in this Challenge.

Challenge Reward: $10,000 USD Deadline: Oct 27, 2009

Enzyme Inhibitors

Thu, 27 Aug 2009 16:52:19 GMT

This Challenge is looking for novel inhibitors of proteases and lipases. This is a Reduction-to-Practice Challenge that requires a written proposal and experimental proof-of-concept data.

Challenge Reward: $35,000 USD Deadline: Nov 27, 2009

Water Problems Affecting People in Developing Countries

Thu, 06 Aug 2009 21:56:09 GMT

Identification of a water-related problem in developing countries that can be the basis of an upcoming InnoCentive Challenge. Problems must be actionable and relatively low cost.

Challenge Reward: $8,000 USD Deadline: Aug 28, 2009

Identification of Specific Lactobacillus Strains in Clinical Samples

Mon, 06 Jul 2009 18:36:06 GMT

This challenge is looking for a method of identification and quantification of specific Lactobacillus strains in clinical samples. This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $8,000 USD Deadline: Aug 20, 2009

Hair Root Removal

Thu, 18 Jun 2009 18:53:15 GMT

This Challenge is looking for new methods of hair root removal. This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $5,000 USD Deadline: Jul 18, 2009

Insulin Delivery System for Developing Countries

Fri, 29 May 2009 18:40:29 GMT

This Challenge is looking for new insulin delivery system for developing world applications. This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Challenge Reward: $5,000 USD Deadline: Jun 29, 2009

Cleaning Process for Infectious Agents

Thu, 21 May 2009 17:26:22 GMT

There is a need for a cleaning process to rid a space (particularly an aircraft) of infectious agents quickly without subsequent damage to existing materials (metals, fabrics, plastics, etc.) including electronic equipment.

This is an Ideation Challenge so your creativity and experience qualify you to participate in this Challenge. Responses are expected to be about 2-3 written pages not including figures.

Challenge Reward: $10,000 USD Deadline: Jul 21, 2009

Lupus Drug Development

Wed, 20 May 2009 20:11:32 GMT

The Seeker is looking for a comprehensive review of the history of Lupus drug development along with actionable recommendations on how this process could be improved. This is a Theoretical Challenge that requires only a written proposal to be submitted.

Challenge Reward: $15,000 USD Deadline: Jul 20, 2009

ALS Biomarker

Fri, 15 May 2009 18:49:10 GMT

Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's Disease) is a fatal neurodegenerative disorder characterized by selective death of motor neurons in the brain and spinal cord. This leads to muscle weakness, atrophy, and gradual paralysis. At present, there is no effective therapy for the disease and patients usually die within 2-5 years after the onset of symptoms. In order to accelerate the identification of effective treatments for ALS, a biomarker for measuring disease progression is needed.

Challenge Reward: $1,000,000 USD Deadline: Jan 24, 2011

Passenger Screening for Contagious Agents

Fri, 01 May 2009 21:05:31 GMT

We are searching for an aircraft pre-boarding passenger screening system that would indicate exposure to or infection by a contagious agent. The pre-clinical, pre-symptomatic medical diagnostic system must be non-invasive to the greatest extent possible. There should be no need for body fluids extraction (i.e. it can be detected from skin, breath, etc.)

Challenge Reward: $25,000 USD Deadline: Jul 01, 2009

Drug localization and quantitation in the retina

Wed, 29 Apr 2009 21:29:31 GMT

A non-invasive method for drug localization and quantitation in the retina is desired.

Challenge Reward: $20,000 USD Deadline: Jun 29, 2009

Sterilization Counter

Wed, 22 Apr 2009 17:35:38 GMT

The Seeker is looking for a method for counting the number of times an object has been sterilized. This is a Theoretical Challenge that requires only a written proposal to be submitted.

Challenge Reward: $20,000 USD Deadline: Jun 22, 2009

Low-cost Rainwater Storage System

Thu, 30 Oct 2008 14:26:19 GMT

EnterpriseWorks/VITA (EWV), is seeking design ideas for a low-cost rain water storage system that can be installed in households in developing countries. The solution is expected to facilitate access to clean water at a household level, addressing a problem that affects millions of people worldwide who are living in impoverished communities or rural areas where access to clean water is limited. Domestic rain water harvesting is a proven technology that can be a valuable option for accessing and storing water year round. However, the high cost of available rain water storage systems makes them well beyond the reach of low-income families to install in their homes.

A solution to this problem would not only provide convenient and affordable access to scarce water resources, but would also allow families, particularly the women and children that are usually tasked with water collection, to spend less time walking distances to collect water and more time on activities that can bring in income and improve the quality of life.

Challenge Reward: $15,000 USD Deadline: Jan 12, 2009

Faster Diagnosis of Viable Microorganisms

Tue, 07 Oct 2008 19:19:18 GMT

The challenge is looking for novel ideas and technologies that can be applied to achieve fast detection and identification of viable microorganisms and determination of antibiotic susceptibility which will enable faster diagnosis of infections caused by bacteria, for example sepsis and tuberculosis, and lead to more effective therapy and better patient outcomes.

Challenge Reward: $5,000 USD Deadline: Nov 07, 2008

Novel approaches/incentives for biomarker research and qualification

Mon, 15 Sep 2008 19:23:28 GMT

Our Seeker Client, FasterCures, a nonprofit organization, is looking for novel approaches/incentives that can reduce the first-mover disadvantage and induce companies to invest more in biomarkers research and qualification, while not limiting their availability to others.

Challenge Reward: $10,000 USD Deadline: Nov 15, 2008

Ideas for Making Long-term Habit Changes in Lifestyle

Mon, 30 Jun 2008 15:13:36 GMT

We are interested in finding ways for people to make long-term habit changes in lifestyle.

This is an Ideation challenge so your creativity and experience qualify you to participate in this challenge. Responses are expected to be about 2 written pages.

Challenge Reward: $20,000 USD Deadline: Jul 31, 2008

Statistical Methods to Predict Clinical Response

Mon, 21 Apr 2008 18:44:30 GMT

The Seeker is looking for a comprehensive approach - perhaps using some data mining tools involving classification and regression trees, cluster analysis, etc. – for each of two related problems. Both problems involve analyzing a wide range of covariates that may help (a) identify sub-groups of patients who have a differential response to treatment, and (b) predict responders and non-responders in clinical trials.

More details are available once you register as an InnoCentive Solver.

Challenge Reward: $10,000 USD Deadline: May 21, 2008

ChangeNow4Health-Innovative Health care Ideas

Mon, 21 Apr 2008 13:12:55 GMT

The Seeker is soliciting ideas for improvements to the United States Health care system. The key requirement is that the idea must be able to be implemented quickly and effectively. This is an Ideation challenge so your creativity and common sense qualify you to participate in this challenge. Please limit your responses to about 2 written pages.

Challenge Reward: $10,000 USD Deadline: Jul 23, 2008

Reducing Risk of Malaria with Solar Powered Device

Mon, 10 Mar 2008 14:01:31 GMT

Design of an affordable solar powered device to prevent and/or limit the spread of malaria is desired.

Challenge Reward: $40,000 USD Deadline: Jun 10, 2008

Estimating prevalence of seizures in schizophrenics

Fri, 07 Mar 2008 18:24:48 GMT

The Seeker is looking for a comprehensive analysis of available data on the prevalence of seizures in patients with schizophrenia as well as the incidence of new seizures in patients taking anti-psychotic medication. This is a theoretical challenge that requires a detailed, written research report.

More details are available once you register as an InnoCentive Solver.

Challenge Reward: $50,000 USD Deadline: Jun 09, 2008

Dry-based biolatrines

Thu, 06 Dec 2007 13:37:08 GMT

A design for dry-based biolatrines for rural schools in Africa is needed. The biolatrines will contribute to efforts to improve sanitation and water preservation in parts of Africa struggling with increased demand for safe water. This challenge is sponsored by the Rockefeller Foundation and requires only a written proposal.

Challenge Reward: $20,000 USD Deadline: Feb 05, 2008

Safe and Economical Synthetic Route for PA-824, a candidate drug for tuberculosis

Thu, 29 Nov 2007 21:10:56 GMT

Theoretical proposals for a safe and economical synthetic route to the shown nitroimidazole are desired. The route you propose should be more economical than the publicly disclosed routes.

The development of PA-824 is being directed by the Global Alliance for TB Drug Development, a not-for-profit, product development partnership accelerating the discovery and development of new TB drugs that will shorten treatment, be effective against susceptible and resistant strains, be compatible with antiretroviral therapies used for HIV/AIDS, and improve treatment of latent infection. The Rockefeller Foundation is sponsoring the current InnoCentive Challenge.

More details are available after you have registered as an InnoCentive Solver.

Challenge Reward: $20,000 USD Deadline: Feb 29, 2008

Rapid Test for Detection of Infection

Thu, 26 Jul 2007 17:16:36 GMT

A rapid test for detection of infection is needed.

More details are available once you register as an InnoCentive Solver.

Challenge Reward: $50,000 USD Deadline: Oct 26, 2007

ALS Biomarker

Mon, 06 Nov 2006 15:02:35 GMT

Prize4Life is sponsoring this challenge which is searching for a biomarker for measuring disease progression in Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's Disease/ Motorneuron Disease).

Challenge Reward: $1,000,000 USD Deadline: Nov 06, 2008