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Challenge Enzyme Inhibitors
Enzyme Inhibitors
STATUS: Awarded
Active Solvers: 266
Posted: Aug 27 2009
Challenge ID: 8740549
 
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Abstract
This Challenge is looking for novel inhibitors of proteases and lipases. This is a Reduction-to-Practice Challenge that requires a written proposal and experimental proof-of-concept data.
Overview
This challenge is looking for novel inhibitors of proteases and lipases involved in the skin degradation process.

The submission to the challenge should include the following:

  1. The detailed characterization of the proposed enzyme inhibitors addressing specific Solution Requirements presented in the challenge description. This description should be accompanied by a well-articulated rationale supported by literature/patent precedents.
  2. Experimental data demonstrating the desired properties of the proposed enzyme inhibitors obtained as described by the Seeker.

The Seeker is not looking for just a review on the subject. The proposed enzyme inhibitors should offer the Seeker “freedom to practice“, i.e. there should be no patents or patent applications preventing the use of the solution. The award is contingent upon the evaluation of the submitted solutions by the Seeker.
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InnoCentive is the global innovation marketplace where creative minds solve some of the world's most important problems for cash awards up to $1 million. Commercial, governmental and humanitarian organizations engage with InnoCentive to solve problems that can impact humankind in areas ranging from the environment to medical advancements.

What is an RTP Challenge?

An InnoCentive RTP (Reduction to Practice) Challenge is a prototype that proves an idea, and is similar to an InnoCentive Theoretical Challenge in its high level of detail. However, an RTP requires the Solver to submit a validated solution, either in the form of original data or a physical sample. Also the Seeker is allowed to test the proposed solution. For details about treatment of IP rights, please see the Challenge-Specific Agreement.

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