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SciBX and InnoCentive Challenge: Identifying Questions Surrounding the Endocytic Uptake of Therapeutics

TAGS:Life Sciences Chemistry
STATUS: Awarded
ACTIVE SOLVERS: 213
POSTED: 5/13/13

SciBX: Science-Business eXchange, a joint publication from the makers of BioCentury®and nature, in collaboration with InnoCentive, is requesting broad input from the scientific community to determine key questions, and to propose experiments for addressing these questions, that could progress understanding of how macrocycles and other large therapeutic molecules can effectively intercept and use the endocytosis process to achieve robust, class-wide cell permeability.  This was identified as one of the key questions at the recent SciBX Summit on Innovation in Drug Discovery & Development in the field of Macrocycles and Constrained Peptides

This is an Ideation Challenge with a guaranteed monetary award for one submitted solution.  In addition to the monetary award, as many as five finalist Solvers may be selected and invited to participate in the 2013 SciBX Innovation Summit (see the Summary below for details).

 

Source: InnoCentive
Challenge ID: 9932820
 
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Challenge Overview

SciBX: Science-Business eXchange, a joint publication from the makers of BioCentury®and nature, in collaboration with InnoCentive, is requesting broad input from the scientific community to determine key questions, and to propose experiments for addressing these questions, that could progress understanding of how macrocycles and other large therapeutic molecules can effectively intercept and use the endocytosis process to achieve robust, class-wide cell permeability.  This was identified as one of the key questions at the recent SciBX Summit on Innovation in Drug Discovery & Development in the field of Macrocycles and Constrained Peptides

This is an Ideation Challenge, which has the following unique features:

  • There is a guaranteed award.  The award will be paid to the best submission as solely determined by the Seeker. There will be a single monetary award of $5,000. 
  • In addition to the cash award, the overall Challenge winner will have the unique opportunity to participate at the 2013 SciBXSummit on Innovation in Drug Discovery & Development in Boston, Massachusetts, USA on October 30, 2013.  This includes registration cost, paid travel to, and accommodations at the event. 
  • As many as five finalist Solvers may be selected and invited to participate in the 2013 SciBX Innovation Summit – SciBX will not cover travel or lodging costs, but will waive the registration fee for these Solvers. 
  • The winning solution(s) will also be prominently featured in an open letter to the Director of the United States National Institutes of Health (and other public and private funding agencies) underscoring the outcomes of the Summit, the results from this Challenge, and the overall importance of this field for translational research. 
  • Solvers are not required to transfer exclusive intellectual property rights to the Seeker.  Rather, by submitting a proposal, the Solvers grant to the Seeker a royalty-free, perpetual, and non-exclusive license to use any information included in this proposal.

After the Challenge deadline, the Seeker will complete the review process and make a decision with regards to the Winning Solution(s).All Solvers that submitted a proposal will be notified on the status of their submissions; however, no detailed evaluation of individual submissions will be provided.

 

What is InnoCentive?
InnoCentive is the global innovation marketplace where creative minds solve some of the world's most important problems for cash awards up to $1 million. Commercial, governmental and humanitarian organizations engage with InnoCentive to solve problems that can impact humankind in areas ranging from the environment to medical advancements. What is an InnoCentive Ideation™ Challenge?

An InnoCentive Ideation™ Challenge is a broad question formulated to obtain access to new ideas, similar to a global brainstorm for producing a breakthrough idea or market survey which may include ideas for a new product line, a new commercial application for a current product, or even a viral marketing idea to recruit new customers. Ideation™ Challenge submissions are typically about two written pages, and Seekers receive a non-exclusive, perpetual license to use all submissions.

In an Ideation™ Challenge, Solvers may:

  • Submit ideas of their own
  • Submit third party information that they have the right to use and further the authority to convey that right and the right to use and develop derivative works to Seekers
  • Submit information considered in the public domain without any limitations on use

Solvers should not reveal any confidential information in their submissions. Often the Ideation™ Challenge will be followed by one or more of the other three Challenge types to further develop the ideas and gain Intellectual Property protection when the concept has been well-defined.

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