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Challenge Understanding Bioavailability of Peptides
Understanding Bioavailability of Peptides
STATUS: Awarded
Active Solvers: 228
Posted: Nov 09 2012
Challenge ID: 9932983
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What sequence and structural factors influence the bioavailability of small peptides following ingestion? Which physiological parameters determine whether peptides reach and persist in the systemic circulation, and which models would be relevant to assess peptide bioavailability? The Seeker is looking for insightful submissions that are supported by peer-reviewed publications, in-silico modelling &/or existing research data. 

This Challenge requires only a written proposal.



Extensively hydrolysed milk proteins are widely used in a range of dietary products, but what is known about the fate of these peptides? What determines efficiency of uptake across the gut epithelium following digestion and their potential activity within the body? 

This challenge is NOT about amino acid uptake mechanisms – it IS about how & why small peptides from bovine milk protein hydrolysates become systemically available. 

This is a Theoretical Challenge that requires only a written proposal to be submitted.  The Challenge award will be contingent upon theoretical evaluation of the proposal by the Seeker. 

To receive an award, the Solvers will not have to transfer their exclusive IP rights to the Seeker.  Instead, they will grant to the Seeker non-exclusive license to practice their solutions. 

What is InnoCentive?
InnoCentive is the global innovation marketplace where creative minds solve some of the world's most important problems for cash awards up to $1 million. Commercial, governmental and humanitarian organizations engage with InnoCentive to solve problems that can impact humankind in areas ranging from the environment to medical advancements.

What is a Theoretical-Licensing Challenge?

An InnoCentive Theoretical Challenge builds upon an idea but is not yet a proof of concept. A solution to a Theoretical Challenge will solidify the Solver's concept with detailed descriptions, specifications and requirements necessary to bringing a good idea closer to becoming an actual product or service.

This Challenge is a Theoretical-Licensing Challenge, meaning that the Seeker is requesting non-exclusive rights to use the winning solution. By contrast, Theoretical-IP Transfer means that Solvers must relinquish all rights to the Intellectual Property (IP) for which they are awarded. For these forms of a Theoretical Challenge, Solvers that do not win retain the rights to their solution after the evaluation period is complete. The Seeker retains no rights to any IP not awarded.

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