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Challenge Pfizer, Neusentis Challenge: Demonstrating Molecular Engagement with an Ion Channel
Pfizer, Neusentis Challenge: Demonstrating Molecular Engagement with an Ion Channel
STATUS: Awarded
Active Solvers: 208
Posted: Sep 16 2013
Challenge ID: 9933445
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Neusentis, a Pfizer Research Unit, desires a novel mechanism for monitoring the interaction between a drug and its targeted ion channel. A solution applicable across all ion channels is desirable, but given the diversity between ion channel families, a proposal specific to a voltage-gated channel is also of interest. Neusentis is interested in identifying potential collaboration partners with novel insights and proposals. 

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.



Drugs targeting ion channels are important therapeutics for patients with cardiovascular, metabolic, and neurological disorders. In order to facilitate the development and advancement of novel therapies, Neusentis desires a method for demonstrating that an ion channel drug is engaged with its target. A universal solution applicable to all ion channels would be ideal. However, there is value in an idea that focuses on major ion channel families (e.g., sodium, potassium, and calcium channels involved in nociceptive action potential generation, transduction and conduction), or a single ion channel target within one of these families. 

This is an Ideation Challenge, which has the following unique features:

  • There is a guaranteed award.  The awards will be paid to the best submission(s) as solely determined by the Seeker. The total payout will be $10,000, with at least one award being no smaller than $5,000 and no award being smaller than $2,000. 
  • The Solvers are not required to transfer exclusive intellectual property rights to the Seeker.  Rather, by submitting a proposal, the Solvers grants to the Seeker a royalty-free, perpetual, and non-exclusive license to use any information included in this proposal, including for promotional purposes.

After the Challenge deadline, the Seeker will complete the review process and make a decision with regards to the Winning Solution(s). All Solvers that submit a proposal will be notified on the status of their submissions; however, no detailed evaluation of individual submissions will be provided.

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InnoCentive is the global innovation marketplace where creative minds solve some of the world's most important problems for cash awards up to $1 million. Commercial, governmental and humanitarian organizations engage with InnoCentive to solve problems that can impact humankind in areas ranging from the environment to medical advancements.

What is an InnoCentive Ideation™ Challenge?

An InnoCentive Ideation™ Challenge is a broad question formulated to obtain access to new ideas, similar to a global brainstorm for producing a breakthrough idea or market survey which may include ideas for a new product line, a new commercial application for a current product, or even a viral marketing idea to recruit new customers. Ideation™ Challenge submissions are typically about two written pages, and Seekers receive a non-exclusive, perpetual license to use all submissions.

In an Ideation™ Challenge, Solvers may:

  • Submit ideas of their own
  • Submit third party information that they have the right to use and further the authority to convey that right and the right to use and develop derivative works to Seekers
  • Submit information considered in the public domain without any limitations on use

Solvers should not reveal any confidential information in their submissions. Often the Ideation™ Challenge will be followed by one or more of the other three Challenge types to further develop the ideas and gain Intellectual Property protection when the concept has been well-defined.

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