Synthesized from polymers, nanofibers have an average diameter of 50 to 1000 nanometers. These fibers are well-suited for tissue engineering since they accurately mimic the fibrous nature of the extracellular matrix produced by cells. Using various techniques, nanofiber drug loading can be accomplished. The Seeker is looking for human diseases or conditions for which the properties of nanofibers could provide a significant advantage over current methods of treatment.
Nanofibers can be used to develop scaffolds that closely resemble the architecture found in cells with similar porosity and elasticity properties to collagen. These nanofibers have high affinity for human tissues and could be used to deliver drugs topically (e.g. sublingual, skin, ophthalmic, etc.) and locally (e.g. tumor, fibrotic tissue, heart, lung, etc.).
This is an Ideation Challenge with a guaranteed award for at least one submitted solution.
Applications for nanofibers in the healthcare arena are comprised of three main categories: tissue engineering, wound healing, and drug delivery. Nanofibers can be used to develop scaffolds that closely resemble the architecture found in cells with similar porosity and elasticity properties to collagen. Nanofiber layers of biopolymers containing antibacterial agents are effective for enhancing the growth of dermal tissue while lowering the risk of infection. Furthermore, active pharmaceutical ingredients incorporated into nanofibers have the potential to deliver drugs topically (e.g. sublingual, skin, ophthalmic, etc.) and locally (e.g. tumor, fibrotic tissue, heart, lung, etc.) based on the high affinity of nanofibers for human tissues. The Seeker is interested in new applications for nanofibers that have yet to be explored. The goal is to identify an unmet need in a human disease or condition and describe how nanofibers would solve the problem in a novel manner.
This is an Ideation Challenge, which has the following unique features:
Submissions to this Challenge must be received by 11:59 PM (US Eastern Time) on April 3, 2015. Late submissions will not be considered.
After the Challenge deadline, the Seeker will complete the review process and make a decision with regards to the Winning Solution(s). All Solvers that submit a proposal will be notified on the status of their submissions; however, no detailed evaluation of individual submissions will be provided.
What is an InnoCentive Ideation™ Challenge?
An InnoCentive Ideation™ Challenge is a broad question formulated to obtain access to new ideas, similar to a global brainstorm for producing a breakthrough idea or market survey which may include ideas for a new product line, a new commercial application for a current product, or even a viral marketing idea to recruit new customers. Ideation™ Challenge submissions are typically about two written pages, and Seekers receive a non-exclusive, perpetual license to use all submissions.
In an Ideation™ Challenge, Solvers may:
Solvers should not reveal any confidential information in their submissions. Often the Ideation™ Challenge will be followed by one or more of the other three Challenge types to further develop the ideas and gain Intellectual Property protection when the concept has been well-defined.