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Challenge Seeking a New Method to Accurately Measure Leg Edema

Seeking a New Method to Accurately Measure Leg Edema

Award: $20,000 USD
STATUS: Under Eval
Active Solvers: 201
Posted: May 21 2018
Challenge ID: 9934024
 
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Abstract

The Challenge to Solvers is to propose a novel method to measure leg edema. A method that is performed in an easy way compatible with daily physician practice during the evaluation of patients suffering from venous disease, and particularly those with leg heaviness symptoms.

This Theoretical Challenge requires only a written proposal.

Overview

The Seeker is a leading player in the treatment and relief of symptoms of patients with chronic venous disease (CVD).  The symptoms, related to various venous conditions, affect up to 30 % of the population and one of the clinical signs of CVD is leg edema - a perceptible increase in the volume of fluid in subcutaneous tissue characterized by indentation under pressure. This increase of fluid and the swelling that may result from it makes the legs feel heavy and affect walking or standing.

The gold standard method to evaluate leg edema in clinical studies and practice is the water volume displacement method (WVD). In this simple but very practical method, the limb is immersed in water and the swelling calculated from the volume of water that is displaced as a result of the immersion. This method has been used with limitations, of which the most relevant are:

  • Variability due to different operators and the conditions in which the test is performed
  • The precision has been estimated to be 0.1 to 1% on repeated tests, which is insufficient to detect clinically relevant changes in the edema volume (down to 20 mL).

Other methods have been attempted and described in the literature but have fallen short. Hence, the objective of this Challenge is to identify a novel solution that can ultimately lead to a method that becomes a new gold standard in clinical practice and clinical studies, allowing for the management of CVD patients, exploring unmet needs in diagnosis, in prognostic, in treatment choices and follow-up.

This is a Theoretical Challenge that requires only a written proposal to be submitted. The Challenge award will be contingent upon theoretical evaluation of the proposal by the Seeker.

To receive an award, the Solvers will have to transfer to the Seeker their exclusive Intellectual Property (IP) rights to the solution. 

Submissions to this Challenge must be received by 11:59 PM (US Eastern Time) on June 25, 2018. 

Late submissions will not be considered.

 

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What is a Theoretical IP Transfer Challenge?

An InnoCentive Theoretical Challenge builds upon an idea but is not yet a proof of concept. A solution to a Theoretical Challenge will solidify the Solver's concept with detailed descriptions, specifications and requirements necessary to bringing a good idea closer to becoming an actual product or service.

This Challenge is a Theoretical-IP Transfer Challenge, meaning that Solvers must relinquish all rights to the Intellectual Property (IP) for which they are awarded. By contrast, Theoretical-Licensing means that the Seeker is requesting non-exclusive rights to use the winning solution. For these forms of a Theoretical Challenge, Solvers that do not win retain the rights to their solution after the evaluation period is complete. The Seeker retains no rights to any IP not awarded.

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