Corteva AgriscienceTM is seeking pure natural products and semi-synthetic natural products for pest control. Material supply of compounds which are natural products or natural-product derived small molecules is desired. Crude extracts and mixtures are not requested for this Challenge.
Intellectual Property: In return for the Initial Transfer Fee of USD $150 per compound (see further details of the Challenge), you are expected to grant the Seeker only a non-exclusive license to test your compound(s) in their in-house assays and/or use the compound(s) to prepare other compounds for in-house testing.
The discovery of novel modes of action for use in crop protection remains an ongoing challenge for multiple reasons, including the increasing demand for higher protein diets, evolution of resistance to existing solutions, and regulatory and societal pressures to continually improve the safety and toxicological profiles of crop protection chemicals. Because bacteria, plants, insects and fungi are in a continual evolutionary and ecological battle in the environment, each species develops its own methods for survival. Some of these tools include the production of small molecules that are generated for a very specific purpose. As farmers seek to find new crop protection solutions to reduce fungal, insect and weed impact on crop yields, there is an opportunity to explore the use of these small molecules developed by nature to improve agriculture.
As the leader in Natural Products Discovery, Corteva AgriscienceTM has historically discovered and developed a number of natural products and semi-synthetic natural products for pest control. However, this discovery process of molecules with novel modes of action is an ongoing challenge in the agricultural industry, and as such we are seeking input from the broader scientific community to gain access to more chemical space; in particular, the biologically relevant space that natural products are known to occupy.
Material supply of compounds which are natural products or natural-product derived small molecules is desired. Crude extracts and mixtures are not requested for this Challenge. Compounds will be strictly filtered for those which adhere to the desired Solution Requirements described in the Detailed Description section of the Challenge. The Seeker intends to award multiple Solvers for each of their qualifying submissions.
By the deadline, Solvers are requested to provide a list of structures which meet the Solution Requirements listed in the Detailed Description of the Challenge. For the structures that are selected by the Seeker, the Solver shall then send in material samples along with documentation including further details as specified in the Detailed Description.
This Challenge is targeting Solvers who:
This Challenge provides Solvers with a three-month time period for preparing the selected compounds after the deadline of the Challenge.
Submissions to this Challenge must be received by 11:59 PM (US Eastern Time) on August 12, 2019.
Late submissions will not be considered.
ABOUT THE SEEKER
Corteva Agriscience™ is the only major agriscience company completely dedicated to agriculture. By combining the strengths of DuPont Pioneer, DuPont Crop Protection and Dow AgroSciences, we've harnessed agriculture's brightest minds and expertise gained over two centuries of scientific achievement. Corteva Agriscience provides growers around the world with the most complete portfolio in the industry — including some of the most recognized brands in agriculture: Pioneer®, Granular®, the newly launched Brevant™ seeds, as well as award-winning Crop Protection active ingredients like Spinosad and Spinetoram — while bringing new products to market through our solid pipeline of active chemistry and technologies. More information can be found at http://www.corteva.com/.
What is an RTP Challenge?
An InnoCentive RTP (Reduction to Practice) Challenge is a prototype that proves an idea, and is similar to an InnoCentive Theoretical Challenge in its high level of detail. However, an RTP requires the Solver to submit a validated solution, either in the form of original data or a physical sample. Also the Seeker is allowed to test the proposed solution. For details about treatment of IP rights, please see the Challenge-Specific Agreement.