Please note that the details of this Challenge are no longer open. This challenge is under evaluation and is no longer accepting new submissions. You can:
Challenge Rapid Detection of Intermolecular Interactions

Rapid Detection of Intermolecular Interactions

Award: $10,000 USD
STATUS: Under Eval
Active Solvers: 339
Posted: Dec 20 2019
Challenge ID: 9934273
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The ability to detect molecular interactions quickly and accurately is essential for the successful interrogation of biological systems and development of new therapeutic drugs. The Seeker is looking for a highly sensitive technique to directly detect a change in a physico-chemical property that results from a molecular interaction in solution.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.


Central to drug discovery is detecting the interaction of a biomolecule (a target, such as a protein or DNA) with a binding partner (ligand). There are many ways to do this, however the most common methods utilize labeling or immobilization of the target molecule. These approaches can be sensitive but may interfere with the results by altering the protein structure. The Seeker desires an innovative, label and immobilization free approach for the rapid detection and quantification of target ligand interactions.

This is an Ideation Challenge, which has the following unique features:

  • There is a guaranteed award.  The award(s) will be paid to the best submission(s) as solely determined by the Seeker. The total payout will be $10,000, with at least one award being no smaller than $5,000 and no award being smaller than $2,000.
  • The Solvers are not required to transfer exclusive intellectual property rights to the Seeker. Rather, by submitting a proposal, the Solver grants to the Seeker a royalty-free, perpetual, and non-exclusive license to use any information included in this proposal, including for promotional purposes.

Submissions to this Challenge must be received by 11:59 PM (US Eastern Time) on February 3, 2020. 

Late submissions will not be considered.

After the Challenge deadline, the Seeker will complete the review process and make a decision with regards to the Winning Solution(s). All Solvers that submit a proposal will be notified on the status of their submissions; however, no detailed evaluation of individual submissions will be provided.

What is InnoCentive?
InnoCentive is the global innovation marketplace where creative minds solve some of the world's most important problems for cash awards up to $1 million. Commercial, governmental and humanitarian organizations engage with InnoCentive to solve problems that can impact humankind in areas ranging from the environment to medical advancements.

What is an InnoCentive Ideation™ Challenge?

An InnoCentive Ideation™ Challenge is a broad question formulated to obtain access to new ideas, similar to a global brainstorm for producing a breakthrough idea or market survey which may include ideas for a new product line, a new commercial application for a current product, or even a viral marketing idea to recruit new customers. Ideation™ Challenge submissions are typically about two written pages, and Seekers receive a non-exclusive, perpetual license to use all submissions.

In an Ideation™ Challenge, Solvers may:

  • Submit ideas of their own
  • Submit third party information that they have the right to use and further the authority to convey that right and the right to use and develop derivative works to Seekers
  • Submit information considered in the public domain without any limitations on use

Solvers should not reveal any confidential information in their submissions. Often the Ideation™ Challenge will be followed by one or more of the other three Challenge types to further develop the ideas and gain Intellectual Property protection when the concept has been well-defined.

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