Economical Testing Set-up for Remanufactured Engines
The Seeker is looking for low cost automotive engine testing equipment that can be used as an alternative to dynamometers and allow to increase the capacity and scale of remanufactured automotive engines performance testing.
This is a Reduction-to-Practice Challenge that requires written documentation and experimental proof-of-concept data.
Pharmaceutical Distribution and Reimbursement Optimization
In the United States, the current pharmaceutical distribution and reimbursement process is complex having multiple third parties involved in the process. This system is highly regulated to ensure that patients have access to medications that have been tested for safety and efficacy, yet the pricing of these pharmaceuticals as well as the logistics of reimbursement leave much to be desired. The Seeker is looking for innovative ways to deliver more value to the patient and to simplify the process by which patients obtain prescription drugs.
This is an electronic Request-for-Partners (eRFP) Challenge; the Solver will only need to submit a written proposal to be evaluated by the Seeker with the goal of establishing a collaborative partnership.
Sandboxing Digital Tools for Clinical Research
The purpose of clinical trials is to determine the safety and efficacy of a medical treatment in humans. These research studies are highly regulated and they require adequate patient enrollment and retention along with rigorous protocols for data gathering. In our connected society, the advent of smartphones and wearable technology makes it is easier than ever to collect data both actively and passively and the expectations of all stakeholders are increasing exponentially. To leverage digital tools in clinical trials, better methods to explore technologies need to be developed that enable rapid business value assessment before they are introduced into formal clinical trials. GSK is seeking collaboration partners who can identify new strategies to quickly and accurately evaluate the value of digital technologies in a simulated clinical research setting.
Novel Intrinsic Biocontainment Methods
Research using viral pathogens is vital to understanding and combating illnesses caused by such viruses and preventing future worldwide pandemics. This research is not without risks and although research facilities that handle dangerous pathogens utilize the most advanced containment equipment and procedures there is still a risk of inadvertent release of such pathogens. Intrinsic biocontainment describes various approaches to deliberately modify a pathogen, and/or a host cell, so that the pathogen does not pose a significant disease risk to humans but retains normal pathological function under specific controlled circumstances. The Seeker is soliciting ideas for novel biocontainment methods that could be used to mitigate the risks associated with research on viral pathogens.
This is an Ideation Challenge with a guaranteed award for at least one submitted solution.
Automated Jewelry Sorting
To ensure that the metal components of jewelry are smooth, shiny, and polished, all items undergo an extensive tumbling process during the production process. There are two steps: raw treatment (disassembled items) and final treatment (assembled items ready for inspection). The Seeker is searching for ways to automatically sort the jewelry components as well as the finished items.
This Theoretical Challenge requires only a written proposal.
Non Invasive Strep Throat and Nasal Pharyngeal Sampling
We are seeking non-invasive ways to collect a bacteria sample from the back of the throat and nasal cavity without causing patient discomfort or gagging.
AstraZeneca Challenge: Enhancing Therapeutic Delivery with Cell-Penetrating Peptides
Cell-penetrating peptides are a special class of molecules that can cross the cell membrane in a receptor-independent manner without inducing toxicity. When coupled with a therapeutic agent, these peptides have the potential to significantly increase cellular uptake and to improve tissue targeted delivery. Preliminary studies indicate that incorporating these peptides into nucleic acid therapeutic molecules and delivery modalities have the ability to improve the efficacy of nucleic acid based therapies. AstraZeneca is seeking collaboration partners who can help us identify novel cell-penetrating peptides capable of overcoming the barriers associated with nucleic acid delivery.
Addictive Jewelry Concepts
We want to push the boundaries of existing jewelry concepts and stretch ourselves in finding new approaches that will inspire and reach more consumers globally. Our consumers are very interested in the latest trends and like to show their unique and personal style with jewelry. The Seeker desires innovative solutions that may help drive consumers to extend their jewelry collections with additional purchases.
Enel Challenge: Improving Short Circuit Power of Battery Energy Storage Systems
The Seeker for this challenge is looking for new power electronic components or balance of plant (BoP) elements related to the inverters to increase short circuit power of battery energy storage systems (BESS), improving their capability to be integrated in the current protection scheme of distribution and transmission networks.
Eradication of Invasive Mussels in Open Water - Stage 1
The Bureau of Reclamation (Reclamation) is seeking innovative solutions to eradicate invasive zebra and quagga mussels from large reservoirs, lakes, and rivers in a cost effective and environmentally sound manner. Invasive mussel infestations pose significant logistical and economic challenges for local communities, recreationists, and water managers. Currently, no practical methods exist for large-scale eradication of invasive dreissenid mussel populations once they become widely established in a reservoir, lake, or river (referred to as “open water”). Solutions can be novel treatments or approaches that build upon existing treatments. This Challenge launches Stage 1 of a planned three-stage Grand Challenge that includes laboratory-scale and field-scale demonstrations.
Challenge Orientation Video: Subject matter experts from Reclamation discuss the need for innovative solutions to eradicate invasive mussels in open water: https://www.youtube.com/watch?v=WWEFlDAUeFQ.
This web site is hosted by a private entity and is not a service of Reclamation or the Department of the Interior (DOI). The solicitation and collection of your personal or individually identifiable information is subject to the host’s privacy and security policies and will not be shared with Reclamation or DOI unless you win the Challenge. To collect an award, Challenge winners’ personally identifiable information must be made available to Reclamation. Please consult the Challenge-Specific Agreement.