Drug Delivery of Large Proteins Through the Urothelium
The bladder is an expandable muscular organ that stores urine before it is excreted. The urothelium lines the surface of the bladder and acts as a protective barrier limiting exposure to toxic substances collected in the urine. In some situations, it is advantageous to administer drugs locally to the bladder lumen. Furthermore, certain diseases of the bladder require delivery of drugs, including therapeutic proteins, to the bladder wall or underlying muscle. Therefore, the Seeker desires a novel technology that can significantly enhance the delivery of large therapeutic proteins through the urothelium.
This Theoretical Challenge requires only a written proposal.
Source: InnoCentive Challenge ID: 9933944
Understanding the Biomechanical Properties of Facial Tissues
The Seeker is looking to identify partners that possess the necessary technical capabilities and expertise to characterize the biomechanical properties of facial tissues with the goal of gaining a deeper understanding of how these tissues contribute to facial structure, expressive movement, and changes with age, leading to the development of next generation medical care.
This is an electronic Request-for-Partners (eRFP) Challenge; the Solver will only need to submit a written proposal to be evaluated by the Seeker with the goal of establishing a collaborative partnership.
Source: InnoCentive Challenge ID: 9933943
RUSAL Challenge: Looking for Joint-Venture Partners for the Production of Goods
RUSAL wishes to leverage the potential of one of its aluminum smelting plants. Located in Nadvoitsy, this plant is equipped with state-of-the-art technology, qualified personnel, unique conditions for energy-intensive production, and is situated in a particularly favorable location classified as a priority area for economic development, therefore benefiting from various incentives to investment.
With that in mind, RUSAL is looking for a partner that can leverage this plant by partnering with RUSAL for the production of new goods, preferably aluminum based but not limited to them.
Source: InnoCentive Challenge ID: 9933923
RUSAL Challenge: Cost-effective Processes to Recover and Recycle Salt from Aluminum Salt Cake (‘Slag’)
Salt cake (‘slag’) is a toxic and hazardous by-product generated during aluminum processing. It is mainly composed by salts (KCl and NaCl) that, instead of being wasted in landfills, can be recovered and re-used in the process. Hence, RUSAL is seeking for a cost-effective process to recover and recycle the salts present in the salt cake.
Source: InnoCentive Challenge ID: 9933959
Advanced Septic Nitrogen Sensor Challenge
The U.S. Environmental Protection Agency (USEPA) (the Seeker) in collaboration with the U.S. Geological Survey (USGS) and The Nature Conservancy (TNC) seeks to identify and spur development of technologies to monitor nitrogen concentration in effluent from advanced Onsite Wastewater Treatment Systems (OWTS). Phase I of this Challenge program is an Ideation Challenge to gain a better understanding of low cost sensor technology that could be utilized to detect and measure nitrate and ammonium, or total nitrogen in the effluent of advanced OWTS. If this initial Ideation is successful, future phases of the Septic Challenge program will include prototype development and testing.
This is an Ideation Challenge with a guaranteed award for at least one submitted solution.
Source: InnoCentive Challenge ID: 9933926
Enel Challenge: Methods to Cool Down Battery Storage Containers
The Seeker for this challenge is looking for an effective way to cost-effectively maintain containers of lithium ion batteries in the optimum temperature range of 15°C to 25°C during operation, guaranteeing the normal operation of the battery cells and a minimum auxiliary power consumption.
Source: InnoCentive Challenge ID: 9933939
Fluid Monitoring in Absorbent Material
The Seeker is looking for Partners who could help develop products, based on their existing products that are “smart” and provide information to the end users on demand. Someone who has knowledge in communication systems based on the “internet of things” is highly desirable. More details will be provided in the details of the Challenge.
This is an electronic Request-for-Partners (eRFP) Challenge; the Solver will only need to submit a written proposal to be evaluated by the Seeker with a goal of establishing a collaborative partnership.
Source: InnoCentive Challenge ID: 9933772
Seeking a New Process for the Production of L-menthol
The production of menthol for industrial applications is based on the extraction of the compound from mint oils, a process that puts a lot of pressure on farming and raises sustainability concerns. Hence, the Seeker is looking for a novel process that can be a more sustainable alternative.
This is a Reduction-to-Practice Challenge that requires submission of written documentation from the Solver. The Seeker will perform experimental validation of proposed solutions in order to determine the award.
Source: InnoCentive Challenge ID: 9933953
Method to Create and Apply Polymer Distribution Profiles
The Seeker is looking for new methods that allow to create distribution profiles of granulate polymers and apply them to surfaces/matrices in continuous production/manufacturing lines.
Source: InnoCentive Challenge ID: 9933949
Measuring the Lipid Composition of a Viral Envelope
Viruses are infectious agents consisting of nucleic acid enclosed within a protein coat known as a capsid. Some viruses also have an outer envelope layer consisting of lipids and proteins. The lipid composition of the viral envelope may impact viral entry into the host cell. Therefore, the Seeker is interested in new approaches to quantitate the lipid content of a population of virus particles.
Source: InnoCentive Challenge ID: 9933914