Indirect Estimates of Reservoir Water Storage
Water storage in reservoirs behind dams is a vital component for water management, and the amount available defines the delivery of benefits from reservoirs. Available water storage, over time, decreases as sediment deposition occurs, thus decreasing the capacity for storage. This sediment deposition, known as sedimentation, also adversely affects reservoir infrastructure operation and maintenance such as outlet works and water intakes. Assessing the loss of storage capacity currently is an expensive and time consuming process performed directly by in-field surveys.
The Bureau of Reclamation, in collaboration with the U.S. Army Corps of Engineers, is seeking a cost effective method to indirectly estimate the storage capacity and/or sediment volume (storage loss) in reservoirs.
This is a Reduction-to-Practice Challenge that requires written documentation, source code, and delivery of an executable application.
This web site is hosted by a private entity and is not a service of the Bureau of Reclamation or the Department of the Interior (DOI). The solicitation and collection of your personal or individually identifiable information is subject to the host’s privacy and security policies and will not be shared with Reclamation or DOI unless you win the Challenge. Challenge winners’ personally identifiable information must be made available to Reclamation in order to collect an award. Please consult the Challenge Specific Agreement.
This Challenge is being conducted by the Seeker under the authority of 15 USC 3719, as amended, which states that cash prize purse awards for this Prize Competition may only be given to an individual that is a citizen or permanent resident of the United States, or an entity that is incorporated in and whose primary place of business is in the United States, subject to verification by the Seeker before Prizes are awarded.
However, submissions can be entertained from all Solvers regardless of whether they are U.S. citizens/entities. Meritorious submissions from non-eligible persons and entities, if any, will be recognized in publications issued by the Seeker announcing the results of the competition, such as press releases. Non-U.S citizens/permanent residents or non-U.S entities can also be included on U.S. teams and are eligible to receive non-cash prize awards, if any. However, cash prize purses will only be awarded to persons and entities eligible to receive cash prize purses under the authority of 15 USC 3719, as amended.
Full eligibility details and other restrictions are detailed in the Challenge Specific Agreement.
Source: InnoCentive Challenge ID: 9933766
Accurate Measurement of Free Drug Concentrations
The drug discovery process is driven by a series of in vitro and in vivo assays to inform the optimization of drug candidates with the ultimate goal of achieving therapeutic efficacy. The percent of total drug present that is not bound to proteins or other cellular components (i.e., the free drug concentration) is thought to correlate with a compound’s pharmacological activity. Therefore, the Seeker is searching for a novel, non-destructive approach for the precise and accurate measurement of free drug concentrations in target tissues.
This Theoretical Challenge requires only a written proposal.
Source: InnoCentive Challenge ID: 9933901
Roche Diabetes Care Challenge
More than 29 million Americans live with diabetes, a metabolic disorder that is characterized by insufficient production or inadequate utilization of insulin resulting in abnormal fluctuations in blood glucose. For diabetics, self-monitoring of blood glucose is essential for knowing when to make therapy adjustments. In the United States, the blood glucose monitoring industry has experienced a negative growth trend despite an increasing number of patients with diabetes. Roche is looking for innovative ideas and solutions that may help a traditional blood glucose manufacturer, like Roche, reverse this trend while meeting patient needs.
This is an Ideation Challenge with a guaranteed award for at least one submitted solution.
Source: InnoCentive Challenge ID: 9933981
Converting Heat Contained in Waste Water Effluents into Forms of Energy for On-site Use
The Seeker is looking to identify processes that can cost-effectively convert the heat contained in hot waste water effluents into forms of energy that can be used to power on-site operations.
Source: InnoCentive Challenge ID: 9933862
Culture of Select Poultry Viruses in Immortalized Cell Substrates
Vaccinations are recommended for people of all ages as a means to prevent infectious diseases by helping the body’s defenses mount an immune response to known pathogens. Many vaccines are produced in chicken eggs with a manufacturing process that has been used for decades. Although high yields are reliably produced, this method is time consuming and expensive, requiring a large number of eggs. Therefore, the Seeker desires a novel approach for culturing viruses in immortalized cell substrates.
The Challenge has a special award structure. A solution proven to be viable for more than one virus will be eligible for multiple awards of $100,000 each.
This is a Reduction-to-Practice Challenge that requires written documentation, experimental proof-of-concept data, and sample delivery.
Source: InnoCentive Challenge ID: 9933916
New Chemistry for Catalytic Metal Ion Deactivation
The Seeker is looking for compounds and chemistry to deactivate metal ions in lubricants, in order to prevent their catalytic effect that leads to oxidation and degradation of lubricants.
Source: InnoCentive Challenge ID: 9933866
LIFT Prize 2017 – Innovation in Postsecondary Learning
Postsecondary learning is increasingly acknowledged as essential for realizing the American dream as more and more opportunities are geared toward highly skilled workers. To close the national talent gap, Lumina Foundation is working towards an equitable, accessible, responsive, and accountable higher education system to increase the proportion of Americans with high-quality degrees, certificates, and other credentials to 60 percent by 2025.
This Challenge requires organizations to submit a completed Application Form, outlining how their entity has a positive impact upon postsecondary attainment in the United States, or how they could transfer their current model to help reach Goal 2025. Entries will be narrowed down to three finalists, who will be invited to a live pitching event at the 1st Annual LIFT Conference from May 11-12, 2017 in Indianapolis, IN. Beyond the award, this prize competition offers an opportunity for visibility and networking with industry leaders.
This Challenge requires the submission of a completed Application Form.
ALERT: New deadline is 11:59 PM (US Eastern Time) on April 2, 2017.
Source: InnoCentive Challenge ID: 9933973
Measuring the Spatial Distribution of Drug Concentrations in Target Tissues
The ability to determine the precise concentration and localization of a drug in target tissues is essential for preclinical research and development. Localization and concentration within the tissue are key parameters used to establish the appropriate dose required to provide adequate drug coverage. Current methods are only capable of determining the total drug concentration within a tissue sample. Therefore, the Seeker desires a new approach for measuring the spatial distribution of drug concentrations in target tissues.
Source: InnoCentive Challenge ID: 9933900
Dining Tables and Chairs to Prevent Sea Sickness in Sailing Ships
The Challenge for Solvers is to describe a dining table and chairs system that can prevent seasickness and minimize the influence of ship movements while navigating at sea.
Source: InnoCentive Challenge ID: 9933972
Predictive Biomarkers for Psoriasis Treatment
Psoriasis is a chronic, inflammatory disease characterized by red, scaly, itchy patches of skin. Although there is currently no cure for psoriasis, patients are prescribed treatments aimed at managing the symptoms, namely regulating the immune system and/or reducing the rapid rate of skin cell proliferation. As new therapies are being developed, it would be helpful to have a method that would predict the effectiveness of these treatments in patients. Therefore, the Seeker desires a biomarker early in the course of therapy that is generalizable and predictive of efficacy later in the course of treatment.
Source: InnoCentive Challenge ID: 9933947