The Seeker aims to identify a detection method that can determine the orientation of a person lying on the top of a plain surface.
This Theoretical Challenge requires only a written proposal.
Source: InnoCentive Challenge ID: 9933758
The increasing use of rooftop solar power generation and other Distributed Energy Resources (DERs) promises to make local utility management much more complex in the coming years. The Seeker is asking for ideas on how to create a system to monitor and manage the complicated utility distribution networks of the future.
This is an Ideation Challenge with a guaranteed award for at least one submitted solution.
Source: InnoCentive Challenge ID: 9933848
Find a fiber based package solution for liquid food products that
The solution should include both materials and processes. More details are provided in the Detailed Description.
Source: InnoCentive Challenge ID: 9933906
The blood-brain barrier (BBB) is an extremely selective filter that excludes many substances from the brain. Besides protecting the brain from toxic insults, the BBB provides a well-defined chemical milieu, which is essential for neuronal function. However, delivering antibody therapeutics across the BBB is a great challenge for treating life-threatening brain diseases like Alzheimer’s or Parkinson’s disease. For example, only 0.1% of a systemically administered antibody reaches the brain of the patient and high doses of the antibody need to be administered to achieve effective therapeutic levels. This can result in serious medical side effects and is economically costly. Therefore, the Seeker seeks novel approaches to deliver an antibody therapeutic across the BBB to the extracellular space of the brain where the drug targets of interest reside.
This is an electronic Request-for-Partners (eRFP) Challenge; the Solver will only need to submit a written proposal to be evaluated by the Seeker with the goal of establishing a collaborative partnership.
Source: InnoCentive Challenge ID: 9933838
Streptococcus suis is not only a pathogenic bacterium that impacts swine production, but it also is a zoonotic agent responsible for an increasing number of human infections in recent years. Preventative treatment of swine herds with vaccines has resulted in relatively low levels of protection. Pigs may also be administered antibiotics, usually of a medically important class, to control infection. Despite the effectiveness of antibiotics for disease prevention, there is pressure to reduce use of these agents in pig farming. Therefore, Elanco desires novel approaches to prevent, treat, or control S. suis infection in swine.
Source: InnoCentive Challenge ID: 9933893
The Seeker is looking to prevent the migration of an amine through a film under harsher than normal conditions (e.g. high temperature). Solutions could take the form of a film change/treatment, a substitute for the amine or anything else that could prevent migration without losing qualities of the product.
Source: InnoCentive Challenge ID: 9933909
Bovine mastitis, an inflammation of the mammary gland due to pathogen invasion, continues to be a main concern in the global dairy industry. Mastitis is the main reason dairy cows are administered antibiotics, and the antibiotics utilized for mastitis treatment and prevention tend to be classified as medically important. In an effort to develop antibiotic alternatives and decrease the amount of antibiotics used for mastitis therapy, Elanco desires a novel solution to prevent, treat, or control mastitis in cattle.
Source: InnoCentive Challenge ID: 9933911
In a world where postsecondary education is essential for being competitive in the job market, less than 40% of adults reach this level of attainment. The statistics are particularly troubling for first in family learners, under-resourced, and lower-income students, military veterans, and adult learners returning to college. For some, life simply gets in the way. For many, a small amount of money will keep students from achieving their dream of college completion. Can we bridge the gap for these individuals while giving universities a better understanding of the persistence probability of the students who are requesting supports? BridgeEdU believes that data-driven emergency financing is an important key and they seek a method to define a new metric to determine which students could benefit the most.
Source: InnoCentive Challenge ID: 9933843
Earlier this year, the American Heart Association (AHA), in partnership with Patient-Centered Outcomes Research Institute (PCORI), conducted a Challenge to hear patients' insights on how health decisions related to heart disease and stroke were made. After patients identified many areas of uncertainty, we are now turning to researchers and clinicians to address several of them through refinement into comparative effectiveness research questions that could benefit from precision medicine approaches. This is an Ideation Challenge with a guaranteed award for four submitters.
Source: InnoCentive Challenge ID: 9933836
The pharmacological effect of inhaled drugs normally correlates with the free drug concentration in the lung tissue. However, accurately determining the free drug concentration of drugs in the relevant lung tissues poses a great challenge to the scientific community. Current methods are rather limited and do not provide the required accuracy that would lead to a sound understanding of drug behavior and pharmacokinetics. Hence, AstraZeneca aims at identifying a novel method that can overcome current limitations.
Source: InnoCentive Challenge ID: 9933829