Coccidiosis Prevention and Control in Poultry
The poultry industry sustains significant losses each year due to coccidiosis. Young birds are especially vulnerable to pathogenic infections as it takes several months for their immune systems to mature after birth. Prevention of coccidiosis can be achieved with drugs that either kill the parasites or prevent their growth and replication within the gastrointestinal tract. The use of anticoccidial medicines has led to drug-resistant strains, therefore, Elanco is searching for novel approaches to prevent, treat, or control coccidiosis in poultry.
A webinar presented by Elanco and InnoCentive concerning Elanco’s Grand Challenge Program was held on October 20, 2016. A recording of the session can be accessed here.
This Theoretical Challenge requires only a written proposal.
Prevention and Control of Enteropathy/Ileitis in Swine
Proliferative enteropathy, commonly known as “ileitis” is the most common enteric disease in pigs. Various antibiotics and vaccination strategies are used to control and treat the disease, but recent changes in regulatory policies and pressure from consumers regarding the use of antibiotics in livestock have increased the need for alternative methods to control the disease. Therefore, Elanco desires novel approaches for the prevention, treatment, or control of proliferative enteropathy in swine.
Liver abscesses are lesions that can develop in all cattle, regardless of age, gender, or breed. Since affected cattle seldom exhibit clinical signs, abscesses are only detected at harvest, where they contribute significantly to loss in carcass value. Although many factors impact the incidence of abscess development, the primary etiological agent is thought to be a bacterial infection. Therefore, cattle are fed tylosin, a broad spectrum, shared-class antibiotic. In an effort to develop antibiotic alternatives, Elanco desires an animal model that recapitulates liver abscess formation in ruminants.