Prevention and Control of Enteropathy/Ileitis in Swine
Proliferative enteropathy, commonly known as “ileitis” is the most common enteric disease in pigs. Various antibiotics and vaccination strategies are used to control and treat the disease, but recent changes in regulatory policies and pressure from consumers regarding the use of antibiotics in livestock have increased the need for alternative methods to control the disease. Therefore, Elanco desires novel approaches for the prevention, treatment, or control of proliferative enteropathy in swine.
A webinar presented by Elanco and InnoCentive concerning Elanco’s Grand Challenge Program was held on October 20, 2016. A recording of the session can be accessed here.
This Theoretical Challenge requires only a written proposal.
Source: InnoCentive Challenge ID: 9933892
Overcoming Key Burden Factors of Patient Participation in Clinical Trials
Deciding to participate in a clinical trial is a complex decision that requires a patient to weigh the pros and cons of potential medical benefit vs. the unknown risks of side effects plus the time, effort and commitment needed to comply with the study protocol. Once in a clinical trial, the burdens of participation may lead to excessive physical and mental stress, which can adversely affect the patient’s well-being and could cause him or her to drop out of a trial prematurely or prevent him or her from enrolling in additional studies. Allergan is committed to improving the patient experience and therefore desires new approaches to overcome key burdens associated with clinical trial participation.
This is an Ideation Challenge with a guaranteed award for at least one submitted solution.
Source: InnoCentive Challenge ID: 9933940
Cordless Power Supply at a Hoist System
The Seeker wishes to identify a cordless (cable-free) power supply system for personnel- and material hoists and the communication between the hoist car and its landing modules. The core Challenge is the cordless power supply of the drive units.
Source: InnoCentive Challenge ID: 9933960
Seeking New Methodologies for Bruiseless Injection
Injection of medical products through the skin almost inevitably leads to bruises in patients. The Seeker to this Challenge wishes to identify novel approaches – devices, chemicals and/or skin treatments – that can significantly reduce or take away the risk of bruises generated by injection.
Source: InnoCentive Challenge ID: 9933903
Substance Delivery Scenarios
The Seeker is looking for novel ways to deliver a substance to a soft surface through a hard protective surface without damaging the hard surface. Solvers are to provide scenarios where a similar problem was solved as potential solutions.
Source: InnoCentive Challenge ID: 9933970
Augmentation of Running/Walking Motion
While running/walking, a person expends about 20% of the energy consumed by the effort of swinging the leg. The Seeker is soliciting ideas to augment this motion to conserve energy with a device/process that could be incorporated into a garment or accessory for the individual. The ideas must reduce the muscular torque needed for running/walking, but not restrict natural motion or have negative effects.
Source: InnoCentive Challenge ID: 9933951
POSCO, a steel company, has developed a lightweight body frame for an electric vehicle called the PBC-EV (POSCO Body Concept – Electric Vehicle). Although they have reduced the body weight by 26%, they have another goal to reduce it by 30% more in the future. POSCO would like to find ideas and technologies that could reduce the body weight of the EV without replacement of the steel by other materials such that they can still meet strict crash requirements. There is a potential for future collaboration of award winners with the Seeker after the Challenge, if interested.
Source: InnoCentive Challenge ID: 9933937
Liver abscesses are lesions that can develop in all cattle, regardless of age, gender, or breed. Since affected cattle seldom exhibit clinical signs, abscesses are only detected at harvest, where they contribute significantly to loss in carcass value. Although many factors impact the incidence of abscess development, the primary etiological agent is thought to be a bacterial infection. Therefore, cattle are fed tylosin, a broad spectrum, shared-class antibiotic. In an effort to develop antibiotic alternatives, Elanco desires an animal model that recapitulates liver abscess formation in ruminants.
Source: InnoCentive Challenge ID: 9933889
The Seeker is searching for new ideas on how to keep track of the evolution of all computer file types from their creation through to their most recent version. Existing metadata representations are not sufficient to include all the information necessary for complete forensic analysis of the history of a file so different ways to collect and store that information is required.
Source: InnoCentive Challenge ID: 9933847
When administering an injection, it is vitally important to have the syringe positioned in the correct location whether that is within a blood vessel or in the surrounding tissue. For example, when insulin is injected into the muscle rather than subcutaneously, the insulin will be used too quickly resulting in dangerously low blood glucose levels. Therefore, the Seeker desires an indicator for proper needle positioning.
Source: InnoCentive Challenge ID: 9933941