Please note that the details of this Challenge are no longer open. This challenge is withdrawn and is no longer accepting new submissions. You can:
Challenge Life Grand Challenge — DNA & RNA Sequencing of a Single Cancer Cell
Life Grand Challenge — DNA & RNA Sequencing of a Single Cancer Cell
Award:  $1,000,000 USD
Deadline: Withdrawn
Active Solvers: 394
Posted: Jun 03 2011
Challenge ID: 9932836
 
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Abstract

The goal of this Life Grand Challenge, sponsored by Life Technologies, is to improve the capabilities of the Next Generation Sequencing technology to reach the ability to monitor the genome and transcriptome derived from a single human cancer cell. 

This is a Reduction-to-Practice Challenge that requires a written proposal and experimental proof-of-concept data.  Please read carefully the Challenge Agreement(entitled Life Technologies Grand Challenge Terms and Conditions).

 

Overview

This Challenge is being run by

The goal of this Life Technologies Grand Challenge is to design a comprehensive molecular biology tool box allowing surveillance of the genome and transcriptome derived from a single human cancer cell. 

The Winning Solution will be determined by a panel of external judges who will perform a detailed evaluation of all experimental data, including a review of the validation data to ascertain that the final submission meets all criteria and requirements set forth in the Detailed Description and Solution Requirements for this Challenge. 

The last date on which validation data can be submitted is November 30, 2012.  

In order to be able to win this Grand Challenge, the Solvers will have to adhere to the following protocol:  

  1. To register on the Life Grand Challenge Website; 
  2. To submit, via the InnoCentive website:
    1. a detailed experimental plan;
    2.  a validation schema; and
    3. completed Legal Documentation. 
  3. Obtain the approval of their experimental plan and, especially, the validation schema by a set of internal judges; 
  4. Execute the experimental schema, obtain results that meet or exceed the requirements set forth in the Detailed Description and Solution Requirements for this Challenge, and validate the obtained results using the approved validation schema; 
  5. Submit validation data via the InnoCentive website

    Internal and external judges will review the submission package and determine whether all the requirements set forth in the Detailed Description and Solution Requirements for this Challenge were met.

  6. In the case of multiple submissions, the following criteria will be implemented to determine which proposal completed the Grand Challenge first.
    1. If Judges deem that all the requirements set forth in the Detailed Description and Solution Requirements for this Challenge have been met, they will issue a dated Completion Letter, establishing date and time of successful completion;
    2. If Judges deem that all the requirements set forth in the Detailed Description and Solution Requirements for this Challenge have NOT been met and request additional data or data validation, then the Judges will issue a dated Completion Letter once all requests have been answered satisfactorily.
    3. The Solver with the earliest dated Completion Letter from the Judges will be considered the Winner of the Challenge.  This Solver would be awarded the grand prize.

The Solvers will also have to agree, upon entry submission, to grant Life Technologies a non-exclusive, fully paid license to any and all intellectual property associated with the submission.  The Winning Solver will assign exclusive ownership of all intellectual property to Life Technologies per the Challenge Agreement and as a condition of collecting the full award. 

What is InnoCentive?
InnoCentive is the global innovation marketplace where creative minds solve some of the world's most important problems for cash awards up to $1 million. Commercial, governmental and humanitarian organizations engage with InnoCentive to solve problems that can impact humankind in areas ranging from the environment to medical advancements.

What is an RTP Challenge?

An InnoCentive RTP (Reduction to Practice) Challenge is a prototype that proves an idea, and is similar to an InnoCentive Theoretical Challenge in its high level of detail. However, an RTP requires the Solver to submit a validated solution, either in the form of original data or a physical sample. Also the Seeker is allowed to test the proposed solution. For details about treatment of IP rights, please see the Challenge-Specific Agreement.

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