Novartis is reimagining medicine to improve and extend people’s lives. As a leading global medicines company, we use innovative science and digital technologies to create transformative treatments in areas of great medical need. In our quest to find new medicines, we consistently rank among the world’s top companies investing in research and development. Novartis products reach nearly 800 million people globally and we are finding innovative ways to expand access to our latest treatments. About 109,000 people of more than 145 nationalities work at Novartis around the world. Find out more at

Why We Are Here

At Novartis, we use science-based innovation to address some of society’s most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible.
Our Open Innovation mission is to deliver transformative innovation. In our pursuit of transformative treatments, we challenge medical paradigms and explore possibilities to cure disease, intervene earlier in chronic illnesses, and find ways to dramatically improve quality of life.

What Challenge will you solve today?

Explore all our Challenges

Increasing Awareness and Testing of a Genetic Risk Factor for Cardiovascular Disease


According to the World Health Organization, cardiovascular diseases (CVDs) are the leading cause of death worldwide.

Development of a Systems Pharmacology Model


Studying the pharmacological effects of drugs injected into the human eye is difficult because traditional sampling methods are invasive. Therefore, the Seeker desires a computational model that accurately simulates the systems pharmacology of an administered drug.

Hypothesis for Causality


An approved medicine has been associated with post-marketing adverse event case reports following administration of the drug in the eye. Novartis is seeking plausible hypotheses for these observations based upon publicly available information.

Here's how the Challenge process works:


Sign up and complete your Solver profile

Review & Accept

Read the description of the Open Challenges in the Challenge Center and accept the Challenge Specific Agreement


Upload proposed solution(s) you have developed for a specific Challenge


Receive cash awards for solutions accepted by Seeker organizations

Join Novartis Oncology at the latest medical congresses

Learn how Novartis is pushing the boundaries with bold science, seeking to transform lives and striving toward cures for patients.

Novartis COVID-19 Information Center

Novartis is responding to the coronavirus disease (COVID-19) outbreak. The information center provides a central hub for news, guidance and resources.

Innovating for challenging healthcare issues

Data and Digital

Embedding data science and digital technologies across Novartis to transform the way we innovate in R&D, run our business operations and engage with HCPs and patients.

Cell & Gene Therapy at Novartis

Our teams aim to deliver on the promise of cell and gene therapy for patients.

Patients & Caregivers

We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible.

Healthcare Professionals

We work closely with healthcare professionals around the world to understand their unmet needs and create innovative programs to support their work.