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Help Reduce the Placebo Effect in Clinical Drug Trials!

59 Submissions
$25,000 USD
Challenge closed

Challenge overview

Markers predictive of placebo-responders in clinical drug trials, or rational for improved trial designs, are required in order to increase the efficacy of clinical drug trials and better understand the effects of human therapies.

This is a Theoretical Challenge that requires only a written proposal to be submitted. The Challenge award will be contingent upon theoretical evaluation of the proposal by the Seeker.
Placebo responses in as many as 60% of the placebo-receiving patients often mask the efficacy of drugs in clinical trials. Biomarkers predictive of placebo responders or new methods of trial design and trial procedure are desired. The biomarker, trial design, or procedure would allow individuals likely to show a placebo-response to be identified and excluded from trials during the patient selection process.

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