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Rapid Detection of Intermolecular Interactions

35 Submissions
$10,000 USD
Challenge closed

Challenge overview

The ability to detect molecular interactions quickly and accurately is essential for the successful interrogation of biological systems and development of new therapeutic drugs. The Seeker is looking for a highly sensitive technique to directly detect a change in a physico-chemical property that results from a molecular interaction in solution.

This is an Ideation Challenge with a guaranteed award for at least one submitted solution.

Central to drug discovery is detecting the interaction of a biomolecule (a target, such as a protein or DNA) with a binding partner (ligand). There are many ways to do this, however the most common methods utilize labeling or immobilization of the target molecule. These approaches can be sensitive but may interfere with the results by altering the protein structure. The Seeker desires an innovative, label and immobilization free approach for the rapid detection and quantification of target ligand interactions.

This is an Ideation Challenge, which has the following unique features:

  • There is a guaranteed award.  The award(s) will be paid to the best submission(s) as solely determined by the Seeker. The total payout will be $10,000, with at least one award being no smaller than $5,000 and no award being smaller than $2,000.
  • The Solvers are not required to transfer exclusive intellectual property rights to the Seeker. Rather, by submitting a proposal, the Solver grants to the Seeker a royalty-free, perpetual, and non-exclusive license to use any information included in this proposal, including for promotional purposes.

Submissions to this Challenge must be received by 11:59 PM (US Eastern Time) on February 3, 2020. 

Late submissions will not be considered.

After the Challenge deadline, the Seeker will complete the review process and make a decision with regards to the Winning Solution(s). All Solvers that submit a proposal will be notified on the status of their submissions; however, no detailed evaluation of individual submissions will be provided.

Use the slider to explore how the Challenge process works:

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